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The 4Cs—Without All Four, You Fall Short

Getting meaningful and actionable metabolomics results requires the 4Cs: coverage, competency, comparability, and capacity.

Coverage

Coverage encompasses the biochemical breadth and diversity that you can detect in your samples. To fully understand your biological systems, you must be able to capture not only endogenous metabolites, those produced by the host, but also exogenous metabolites. Why?

Exogenous metabolites are particularly powerful, because they reveal how a system (the human body, for example) reacts to the environment. Exercise, what we eat and drink, the medications we take, everything impacts the human body and can be important indicators of health and disease.

That’s why at Metabolon, we’ve developed our technology to enable you to see and compare thousands of metabolites in a single sample. With such comprehensive coverage, you’ll never miss out on important insights.

Poor Metabolomics Coverage Limits Biological Understanding
Intelligent Study Design

Competency

Competency is the ability to generate high-quality data and interpret the biological results. Crucial to this ability is knowledge of the pitfalls that can occur during a metabolomics study so they don’t happen to you.

At Metabolon, we have a thorough understanding of the pitfalls that can plague any study of any size and on any host. Through over 10,000 projects, we’ve gained the competency required to avoid the pitfalls that can make biological insights possible. We generate high-quality data and can help you interpret it so you can maximize the potential insights from your metabolomics studies.

Comparability

Comparability is where the true power of metabolomics lies. The ability to cross-compare hundreds of thousands of metabolomics samples from different researchers, times, geographies, patients, and matrices will drive innovation in human healthcare in ways we can’t yet imagine.

Achieving this level of comparability is not easy—but at Metabolon, we’ve developed the technology required for you to add your metabolomics datasets to an ever-growing bank of metabolomics insights and to draw from those insights to make your studies even more impactful.

Broad Coverage Leads to Actionable Insights
Capacity

Capacity

Capacity—the ability to process hundreds of thousands of samples quickly and cost-effectively—is the answer for researchers tired of waiting “just a little longer” for results to come back from a collaborating lab. With the pace of modern research, anyone left with unpredictable turn around times just can’t keep up.

At Metabolon, our Client Success team manages sample shipping to ensure study success. Predictable turnaround times make sure you know what to expect and when to expect it and make sure you’re never left behind waiting for data.

Our Commitment to Quality

We can offer you the complete mixture of coverage, competency, comparability, and capacity because of our commitment to quality. We operate using procedures established in our Quality Management System to ensure that our complex deliverables are accurate and consistent. At every stage, we deliver robust quality assurance and quality control with a rigorous data governance program and adherence to valued U.S. federal and international standards and regulations.
Our Commitment to Quality

See how Metabolon can advance your path to preclinical and clinical insights

Why Metabolon?

Once you see the full value of metabolomics, the only remaining question is who does it best? While many laboratories have metabolite profiling or analytical chemistry capabilities, comprehensive metabolomics technologies are extremely rare. Accurate, unbiased metabolite identification across the entire metabolome introduces signal-to-noise challenges that very few labs are equipped to handle. Also, translating massive quantities of data into actionable information is slow, if not impossible, for most because proper interpretation takes two things that are in short supply: experience and a comprehensive database.

Only Metabolon has all four core metabolomics capabilities

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Coverage

Ability to interrogate thousands of metabolites across diverse biochemical space, revealing new insights and opportunities

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Comparability

Ability to integrate the data from different studies into the same dataset, in different geographies, among different patients over time

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Competency

Ability to inform on proper study design, generate high‐quality data, derive biological insights, and make actionable recommendations

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Capacity

Ability to process hundreds of thousands of samples quickly and cost‐efficiently to service rapidly growing demand

Partner with Metabolon to access:

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A library of 5,400+ known metabolites, 2,000 in human plasma, all referenced in the context of biochemical pathways

  • That’s 5x the metabolites of the closest competitor
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Unparalleled depth and breadth of experience analyzing and interpreting metabolomic data to find meaningful results

  • 10,000+ projects with hundreds of clients
  • 2,000+ publications covering 500 diseases, including numerous peer-reviewed journals such as Cell, Nature and Science
  • Nearly 40 PhDs in data science, molecular biology, and biochemistry

Using our robust platform and visualization tools, our experts are uniquely able to tell you more about your molecule and develop assay panels to help you zero in on the results you need.

Contact Us

Talk with an expert

Request a quote for our services, get more information on sample types and handling procedures, request a letter of support, or submit a question about how metabolomics can advance your research.

Corporate Headquarters

617 Davis Drive, Suite 100
Morrisville, NC 27560

Mailing Address:
P.O. Box 110407
Research Triangle Park, NC 27709

+1 (919) 572-1721