About Exploratory Panels
Absolute quantification of any analyte, in any sample, anytime—All Metabolon Target targeted panels and assays are available to purchase as Exploratory Panels.
An Exploratory Panel allows customers to leverage Metabolon’s expertly developed and validated methods in any exploratory matrix, giving you immediate access to high-quality, rigorously tested, optimized, and calibrated methodology as the foundations for your study using any sample type.
Explore Functional Phenotype In Any Biological Sample
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|Opuntia (Cactus)||Orange||Oryza Sativa (Rice)||Palm|
|Adrenal Gland||Amniotic Fluid||Aqueous Humor||Ascites|
|BALF||Bile||Bone Marrow||Breast Milk|
|Breath Condensate||Cartilage||Colon||Dried Blood Spots|
|Endometrium||Fallopian Tube||Feces||Hair Follicles|
|Vitreous Fluid||Whole Blood|
|Horse||Insect (various)||Lobster||Mollusk (various)|
|Rabbit||Rat||Reptile (various)||Sea Urchin|
|Cell Media||Fungus (Yeast)||Hydrolysates||Mammalian Cells (CHO, HELA, Lymphocytes, RBC, etc.)|
|Non-Mammalian Cells (Bacteria, etc.)||Organoids||Phytoplankton|
Validating the Non-Validated
While unlikely, using a validated methodology with a non-validated matrix may inflate the signal-to-noise ratio (SNR), complicating the analysis of your samples. To ensure the data we collect for your study is accurate and meets Metabolon’s quality standards for all validated Metabolon Target panels, we may ask you to first participate in an initial pilot study. This will give you an early indication of the ability of the combination of our panel and your chosen matrix to potentially detect, identify, and quantify biomarkers, allowing us to proceed with your full study with confidence.
Sample Matrix Validation Services
We partner with businesses and institutions to develop targeted metabolomics services for all research areas and commercial objectives. If your study relies on a specific matrix or a unique set of analytes, inquire about our Sample Matrix Validation or Custom Method Development services. Any validation or development request will be tailored to your needs and ensure the highest possible accuracy, quality, and reproducibility for your current and future projects.
Delivering Absolute Quantification for Research and Biomarker Analysis
Our readily available or custom developed quantitative assays help you achieve your research and biomarker validation objectives with precise and fully validated methods. Our targeted assays and panels cover >1,000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways, and physiological processes, and they can be customized to best fit any application.
Sample Matrix Validation Details
Our Quality—ISO 9001:2015 Certified Laboratory
Metabolon offers three levels of sample validation: Exploratory (research-oriented, limited validation), RUO (Routine Use Only), and GCP/GCLP (Good Clinical Practice / Good Clinical Laboratory Practice).
All methods at Metabolon are validated to adhere to Metabolon’s ISO 9001:2015 certified quality system. Validation experiments are based on the FDA, EMA, and ICH M10 Bioanalytical Guidance documents. All data are peer-reviewed, and a summary report containing the results of the validation experiment is provided.
For GCP/GCLP validation, all experiments and acceptance criteria strictly adhere to the FDA, EMA, and ICH M10 Bioanalytical Guidances. All GCP/GCLP studies are peer-reviewed and audited by the Metabolon Quality Assurance Department. A validation report containing all of the elements listed in the M10 Bioanalytical Guidance is provided.
The table below outlines all evaluated analytical performance parameters for Exploratory, RUO, and GCP/GCLP standards.
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|Method Validation Offerings|
|Linearity, Accuracy, and Precision of Calibration Standards||✓ (1 run)||(3 runs)||(3 runs)|
|QC Precision Accuracy||✓||✓ (3 levels)||✓ (3 levels)|
|Lower Limit of Quantitation||✓ (1 run)||✓ (3 runs)||✓ (3 runs)|
|Selectivity||✓ (1 run)||✓ (3 runs)||✓ (3 runs)|
|Carryover||✓ (1 run)||✓ (3 runs)||✓ (3 runs)|
|Extraction Recovery (also used to show accuracy)||✕||✓||✓|
|Sample Stability Testing – Benchtop Stability||✕||✓||✓|
|Sample Stability Testing – Freeze/Thaw Stability||✕||✓||✓|
|Matrix Effect Testing||✕||✕||✓|
|Sample Stability Testing – Long-Term Stability||✕||✕||✓|
|Extract Stability Testing||✕||✕||✓|
|Run Injection Stability Testing||✕||✕||✓|
|Solution Stability Testing||✕||✕||✓|
Big Insights with Metabolon
Cited in over 3,000 publications, we help scientists and manufacturers gain greater insight into their studies through metabolomics. See how our approach can become a successful part of your workflow.
Related Metabolomics Resources
Talk with an expert
Request a quote for our services, get more information on sample types and handling procedures, request a letter of support, or submit a question about how metabolomics can advance your research.
617 Davis Drive, Suite 100
Morrisville, NC 27560
P.O. Box 110407
Research Triangle Park, NC 27709
+1 (919) 572-1711