ABOUT METABOLOMICS
Small molecules
big insights
Metabolomics provides a unique, real-time fingerprint of your biological system to reveal novel discoveries and realize the promise of precision medicine.
Drug Development
Identify, clarify, confirm
Novel drug development is riddled with scientific uncertainties and financial risk. Metabolomics can improve your program’s chance for success by providing a comprehensive methodology to precisely illuminate the impact of your molecule in vivo and accelerate the drug development process.
Identify novel pharmacodynamic, efficacy, and response biomarkers
Clarify or define the mechanism of action (MOA)
Triangulate upstream gene expression and downstream metabolite function to confirm individual biochemical pathways in response to your molecule
Microbiome
Crack the functional code
Genomic sequencing can reveal microbiome richness and diversity – which and how many microbes are present in a microbiome – but stops short of revealing how microbes behave or their interaction with the host. Metabolomics reveals the critical next level of understanding by providing an instantaneous snapshot of microbial function, its impact on the host, and response to therapeutic intervention.
GWAS
Build a Disease Atlas
Determining gene function and ascertaining important allelic differences are great challenges in genomic research. Metabolites are a sensitive and strong link between genes and disease phenotypes. Genomics researchers who incorporate metabolomics into GWAS studies can identify the allelic differences that matter and their mechanistic role in complex traits. The use of metabolomics increases understanding of disease and helps identify new opportunities for therapeutic intervention.
