New to metabolomics? Start here:
Your Introductory Guide to Metabolomics
This is a comprehensive guide developed to teach you the ins and outs of one of the most powerful omics tools in any scientist’s toolbox, one that can complement any existing workflow and help realize the full potential of other omics methods: metabolomics.
Designing a Successful Metabolomics Study
Metabolites have a wide range of functions, including cell growth support, defense and inhibition, and stimulation. They include amino acids, alcohols, vitamins, polyols, organic acids, and many other types of molecules, and are often the building blocks for larger compounds.
Drug Development Metabolomics
Identify, clarify, confirm
Novel drug development is riddled with scientific uncertainties and financial risk. Metabolomics can improve your program’s chance for success by providing a comprehensive methodology to precisely illuminate the impact of your molecule in vivo and accelerate the drug development process.
Identify novel pharmacodynamic, efficacy, and response biomarkers
Clarify or define the mechanism of action (MOA)
Triangulate upstream gene expression and downstream metabolite function to confirm individual biochemical pathways in response to your molecule
Crack the functional code
Genomic sequencing can reveal microbiome richness and diversity—which and how many microbes are present in a microbiome—but stops short of revealing how microbes behave or their interaction with the host. Metabolomics reveals the critical next level of understanding by providing an instantaneous snapshot of microbial function, its impact on the host, and response to therapeutic intervention.
Build a Disease Atlas
Determining gene function and ascertaining important allelic differences are great challenges in genomic research. Metabolites are a sensitive and strong link between genes and disease phenotypes. Genomics researchers who incorporate metabolomics into GWAS studies can identify the allelic differences that matter and their mechanistic role in complex traits. The use of metabolomics increases understanding of disease and helps identify new opportunities for therapeutic intervention.
Related Metabolomics Resources
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