The Beauty of Understanding the Science
There is a science to developing effective personal care and cosmetic products. From vitamin-enriched moisturizers and collagen lipsticks to tooth-whitening products and antiperspirants, metabolomics holds the key to validating that your products are safe and effective and that your claims are true.
As of 2019, the global beauty industry was worth $532 billion.1 Let our metabolomics solutions for personal care offerings and cosmetics help you develop better quality products and make your unique selling proposition more competitive.
Developing Tailored Personal Care and Cosmetic Products
Providing a Comprehensive Survey of Human Biology
The Metabolon Global Discovery Panel can provide deep insight into an array of biological processes surrounding skin, hair, oral, and ocular health. It can provide a high-fidelity and reproducible analysis of a biological sample’s metabolomic profile.
At Metabolon, we believe metabolomics produces critical insights into what a healthy skin microbiome is doing and how balance can be restored to unhealthy skin. In the past, studying the skin metabolome required invasive techniques such as a punch biopsy. Metabolon’s technology can provide a comprehensive survey of the skin metabolome from a range of non-invasive skin sampling options, such as skin tapes combined with a proprietary sample preparation process.
Furthermore, with Metabolon’s unbiased metabolomic profiling, saliva can be leveraged as a clinical tool because of its potential to mirror oral health conditions, such as periodontal disease.
In addition to the Metabolon Global Discovery Panel, we can quantitatively measure hundreds of lipid analytes on our pre-existing skin lipid panels. Combined, lipidomics and metabolomics can capture biomarkers of wound repair, UV exposure, hydration, environmental exposures, oral health, and more.
Supporting Each Step of your Development Process
Metabolomics and lipidomics have the capability to answer fundamental questions to help deliver safe and effective beauty products. Metabolon’s global metabolomics technology can detect and identify 5,400+ metabolites from skin, saliva, hair, and tear samples. Metabolon’s technology has already helped researchers understand conditions as diverse as dandruff, atopic dermatitis, psoriasis, acne, periodontal disease, and aging.
To accelerate personal care and cosmetics research, the challenge now is to combine these new metabolomic and lipidomic data streams with host genetics and microbial metagenomics across diverse populations. This knowledge will transform our ability to correct a particular skin, hair, or oral conditions. It will also set a scientific standard to deliver more personalized personal care and cosmetic products.
At Metabolon, we realize the importance of metabolomics in understanding skin biology and have invested a tremendous effort in developing methods and tools for skin research. The tools we use for skin analysis will not only promote a better understanding of the basic principles governing skin biology but will also become a frontline approach for understanding the complex interaction between the host and microbiota that govern skin health.
See how Metabolon can advance your path to preclinical and clinical insights
Metabolomics Panels for Cosmetics Applications
Sebum Targeted Panel
Stratum Corneum Targeted Panel
Tryptophan/Kynurenine Ratio Targeted Panel
The kynurenine pathway is a metabolic pathway leading to the production of nicotinamide adenine dinucleotide (NAD+) from the enzymatic conversion of tryptophan. Immune activation leads to the formation of kynurenine with corresponding loss of tryptophan. The kynurenine/tryptophan ratio has been used to reflect the activity of the tryptophan-degrading enzyme indoleamine 2,3-dioxygenase (IDO) in cellular inflammatory response related to symptoms of depression, schizophrenia, and other neurological diseases.
Metabolon in Action
The Link Between Circadian Rhythm and Metabolic Disease
Pollution Exposure and Skin Diseases
Periodontal Disease and Diabetes Biomarkers
Diabetes increases the risk for periodontitis, and the severity of periodontitis has been shown to have a negative effect on glycemic control. The study provides a catalog of salivary metabolites that reflect diabetic changes and provide insight into the underlying link between periodontitis and diabetes.
Interested in Further Studies?
Once you see the full value of metabolomics, the only remaining question is who does it best? While many laboratories have metabolite profiling or analytical chemistry capabilities, comprehensive metabolomics technologies are extremely rare. Accurate, unbiased metabolite identification across the entire metabolome introduces signal-to-noise challenges that very few labs are equipped to handle. Also, translating massive quantities of data into actionable information is slow, if not impossible, for most because proper interpretation takes two things that are in short supply: experience and a comprehensive database.
Only Metabolon has all four core metabolomics capabilities
Ability to interrogate thousands of metabolites across diverse biochemical space, revealing new insights and opportunities
Ability to integrate the data from different studies into the same dataset, in different geographies, among different patients over time
Ability to inform on proper study design, generate high‐quality data, derive biological insights, and make actionable recommendations
Ability to process hundreds of thousands of samples quickly and cost‐efficiently to service rapidly growing demand
Partner with Metabolon to access:
A library of 5,400+ known metabolites, 2,000 in human plasma, all referenced in the context of biochemical pathways
- That’s 5x the metabolites of the closest competitor
Unparalleled depth and breadth of experience analyzing and interpreting metabolomic data to find meaningful results
- 10,000+ projects with hundreds of clients
- 2,000+ publications covering 500 diseases, including numerous peer-reviewed journals such as Cell, Nature and Science
- Nearly 40 PhDs in data science, molecular biology, and biochemistry
Using our robust platform and visualization tools, our experts are uniquely able to tell you more about your molecule and develop assay panels to help you zero in on the results you need.
Related Personal Care & Cosmetics Metabolomics Resources
Talk with an expert
Request a quote for our services, get more information on sample types and handling procedures, request a letter of support, or submit a question about how metabolomics can advance your research.
617 Davis Drive, Suite 100
Morrisville, NC 27560
P.O. Box 110407
Research Triangle Park, NC 27709