Metabolites that Translate Microbial Activity into Host Impact

Microbiome research is now established as one of the most crucial areas of scientific exploration, as it uncovers the profound influence microorganisms have on host health, disease, treatment response and overall well-being. The microbiome’s capacity to generate a vast repertoire of metabolites has profound implications for health and disease. These microbial metabolites are key mediators of microbiome-host interactions, influencing various physiological and pathological processes.

To help researchers understand the functional outputs of microbiome activity, Metabolon designed a carefully curated panel of metabolites that reports on microbiome activity. The Microbiome Panel screens for 400 microbiome-associated metabolites that were vetted in scientific literature as microbiome-relevant, covering key biology that span dozens of chemical classes. Short Chain Fatty Acids are measured with rigorous absolute quantitation within the Microbiome Panel, enabling comparison of these microbially-derived and clinically relevant biomarkers to values reported in the literature. Collectively, these metabolites report on key outputs of microbial activity, moving beyond just characterizing the microbial community composition of a sample into measuring the molecules they produce that influence host physiology.