Publications

Metabolon’s established expert view on metabolomics has been published in 2,000+ publications. Below is a curated selection of high-impact studies.

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Metabolome modulation of the host adaptive immunity in human malaria

Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease

Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes

Combined Metabolic Activators Reduces Liver Fat in Nonalcoholic Fatty Liver Disease Patients

Metabolic Alterations in Older Women With Low Bone Mineral Density Supplemented With Lactobacillus reuteri

Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy

Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction

An ambient-temperature storage and stabilization device performs comparably to flash-frozen collection for stool metabolomics in infants

Distinct lipid profile, low-level inflammation, and increased antioxidant defense signature in HIV-1 elite control status

Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Metabolomic Differences Between Critically Ill Women and Men

Lipid Profiles and Heart Failure Risk: Results From Two Prospective Studies

Use of Shotgun Metagenomics and Metabolomics to Evaluate the Impact of Glyphosate or Roundup MON 52276 on the Gut Microbiota and Serum Metabolome of Sprague-Dawley Rats

Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans

Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVD-19

Stratum corneum lipidomics analysis reveals altered ceramide profile in atopic dermatitis patients across body sites with correlated changes in skin microbiome

Serum untargeted metabolomic changes in response to diet intervention in dogs with preclinical myxomatous mitral valve disease

APOE genotype-dependent pharmacogenetic responses to rapamycin for preventing Alzheimer’s disease

Docosahexaenoate-enriched fish oil and medium chain triglycerides shape the feline plasma lipidome and synergistically decrease circulating gut microbiome-derived putrefactive postbiotics

Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma

Metabolomic Profiles of Overweight/Obesity Phenotypes During Adolescence: A Cross-Sectional Study in Project Viva

Precision of a Clinical Metabolomics Profiling Platform for Use in the Identification of Inborn Errors of Metabolism

Methyl Donor Deficiency Blocks Colorectal Cancer Development by Affecting Key Metabolic Pathways

Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance

Prospective serum metabolomic profiling of lethal prostate cancer

Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites

Blood metabolome predicts gut microbiome α-diversity in humans

Plasma Metabolic Signature and Abnormalities in HIV-Infected Individuals on Long-Term Successful Antiretroviral Therapy

Potential roles of gut microbiome and metabolites in modulating ALS in mice

Fish-oil supplementation in pregnancy, child metabolomics and asthma risk

Deleterious mutations in ALDH1L2 suggest a novel cause for neuro-ichthyotic syndrome

Human Breast Milk Promotes the Secretion of Potentially Beneficial Metabolites by Probiotic Lactobacillus reuteri DSM 17938

Physiological and Molecular Dissection of Daily Variance in Exercise Capacity

Maternal obesity and the human milk metabolome: associations with infant body composition and postnatal weight gain

Metabolic profiling in children with autism spectrum disorder with and without mental regression: preliminary results from a cross-sectional case-control study

Metabolomic markers of healthy dietary patterns in US postmenopausal women

Metabolomic analysis of male combat veterans with post-traumatic stress disorder

Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk

Metabolite changes in blood predict the onset of tuberculosis

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1

Metabolomics in the clinic: A review of the shared and unique features of untargeted metabolomics for clinical research and clinical testing

GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients with Nonalcoholic Fatty Liver Disease

Genetics of NAFLD in Twins Consortium. Link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

A Metabolomics Analysis of Body Mass Index and Postmenopausal Breast Cancer Risk

Development of a chemically defined platform fed-batch culture media for monoclonal antibody-producing CHO cell lines with optimized choline content

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia

A wellness study of 108 individuals using personal, dense, dynamic data clouds

A novel Alzheimer’s disease drug candidate targeting inflammation and fatty acid metabolism

Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

Persistent microbiome alterations modulate the rate of post-dieting weight regain

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

Loss-of-function variants influence the human serum metabolome

Two Healthy Diets Modulate Gut Microbial Community Improving Insulin Sensitivity in a Human Obese Population

Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism

Plasma metabolomic profiles enhance precision medicine for volunteers of normal health

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

An atlas of genetic influences on human blood metabolites

Human metabolic individuality in biomedical and pharmaceutical research

Detrimental effects of adenosine signaling in sickle cell disease

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