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Exploratory & Validated Panels

Metabolon Target

Validated Panels

R Absolute Quantitation

R Rigorous Quality Control

R End-to-end Service

About Validated Panels

With more than 20 validated panels and single analyte assays providing absolute, reproducible quantification for more than 450 biochemicals in a variety of different matrices, Metabolon provides the best possible coverage for analytes and biomarkers of significance for all applications and therapeutic areas.

When you purchase any Metabolon Target targeted panel or assay, you benefit from the rigor and expertise of Metabolon’s metabolomics specialists. Every method is fully validated covering precision, accuracy, extraction recovery, carryover, selectivity, benchtop stability, and freeze/thaw stability. This enables you to be confident in the quality and reliable nature of your data, letting you focus on identifying important scientific insights.

Validated Targeted Panels and Assays

The table below is a summary of our most popular validated panels, providing quantification for a series of analytes and biomarkers in various sample types.

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Validated Panels
Service Name Biomarkers Cells Tissue Plasma Serum Urine Feces Feces (OMNImet®•GUT tubes) Dried Blood Spots Saliva Sebum (Sebutape® strips) Stratum Corneum (D-Squame® discs)
Amino Acids Targeted Panel 22
Beta-hydroxybutyrate (BHBA) Single Analyte Assay 1
Bile Acids Targeted Panel 21
C4 Single Analyte Assay 1
Cannabinoids Targeted Panel 31
Central Carbons Targeted Panel 7
Complex Lipids Targeted Panel 1100
Creatinine Single Analyte Assay 1
Diabetes Research Markers Targeted Panel 22
Fatty Acids Metabolism Targeted Panel 26
Free Fatty Acids Targeted Panel 7
Impaired Glucose Tolerance Targeted Panel 8
Indoles/Uremic Toxicity Targeted Panel 6
Insulin Resistance Targeted Panel 4
Lipid Mediators of Inflammation Targeted Panel 57
Metal Analysis Targeted Panel 23
Oxysterols Targeted Panel 12
Salivary Glucose Single Analyte Assay 1
Sebum Targeted Panel 944
Short Chain Fatty Acids Targeted Panel 9
Sphingolipids Targeted Panel 56
Stratum Corneum Targeted Panel 350
Tryptophan/Kynurenine Ratio Targeted Panel 2

Delivering Absolute Quantification for Research and Biomarker Analysis

Our readily available or custom developed quantitative assays help you achieve your research and biomarker validation objectives with precise and fully validated methods. Our targeted assays and panels cover >1,000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways, and physiological processes, and they can be customized to best fit any application.

Validated Panels Details

Our Quality—ISO 9001:2015 Certified Method Development

Achieving absolute quantification for a panel of biomarkers in a reproducible, cost-effective manner is heavily dependent on the quality of the method and technologies being used. Metabolon offers three levels of sample validation: Exploratory (research-oriented, minimal validation), RUO (Routine Use Only), and GCP/GCLP (Good Clinical Practice / Good Clinical Laboratory Practice).

All methods at Metabolon are validated to adhere to the ISO-9001:2015 certified quality system. Validation experiments are based on the FDA, EMA, and ICH M10 Bioanalytical Guidance. All data are peer-reviewed, and a summary report containing the results of the validation experiment is provided.

For GCP/GCLP validation, all experiments and acceptance criteria strictly adhere to the FDA, EMA, and ICH M10 Bioanalytical Guidance. All GCP/GCLP studies are peer-reviewed, and audited by the Metabolon Quality Assurance Department. A validation report containing all of the elements listed in the M10 Bioanalytical Guidance is provided.

The table below outlines all evaluated parameters for Exploratory, RUO, and GCP/GCLP standards.

ISO 9001

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Method Validation Offerings
Evaluated Parameters Exploratory RUO GCP/GCLP
Linearity, Accuracy, and Precision of Calibration Standards ✓ (1 run) (3 runs) (3 runs)
QC Precision Accuracy ✓ (3 levels) ✓ (3 levels)
Lower Limit of Quantitation ✓ (1 run) ✓ (3 runs) ✓ (3 runs)
Selectivity ✓ (1 run) ✓ (3 runs) ✓ (3 runs)
Carryover ✓ (1 run) ✓ (3 runs) ✓ (3 runs)
Dilution Accuracy
Extraction Recovery (also used to show accuracy)
Sample Stability Testing – Benchtop Stability
Sample Stability Testing – Freeze/Thaw Stability
Secondary Instrument
Matrix Effect Testing
Sample Stability Testing – Long-Term Stability
Extract Stability Testing
Run Injection Stability Testing
Solution Stability Testing
QA Review

Big Insights with Metabolon

Cited in over 3,000 publications, we help scientists and manufacturers gain greater insight into their studies through metabolomics. See how our approach can become a successful part of your workflow.

Contact Us

Talk with an expert

Request a quote for our services, get more information on sample types and handling procedures, request a letter of support, or submit a question about how metabolomics can advance your research.

Corporate Headquarters

617 Davis Drive, Suite 100
Morrisville, NC 27560

+1 (919) 572-1721