Stratum Corneum Targeted Panel
Rigorous Quality Control
About Stratum Corneum
Metabolomics reveals biological insights otherwise unseen. For a successful metabolomics study, both small molecule discovery and the ability to dig deeper into specific biomarkers of interest are needed to uncover actionable insights that propel new therapeutic developments. A specific combination of liquid chromatography-mass spectrometry (LC-MS) technology and expertise is required to identify these biomarkers of interest and develop assays that are sensitive enough to explore them fully.
At Metabolon, we understand the crucial role lipids play in skin disorders, and we’ve established best-in-class expertise for their detection. This panel focuses on specific lipids and their metabolic pathways and can be used to track biomarkers and enhance biological understanding across clinical research.
Stratum Corneum Targeted Panel Details
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|Sphingoid Base||Fatty Acid Class|
|Ceramides||alpha-hydroxy fatty acids (AS)|
|esterified omega fatty acids (EOS)|
|saturated fatty acids (NS)|
|Dihydro-ceramides||alpha-hydroxy fatty acids (ADS)|
|saturated fatty acids (NDS)|
|6-Hydroxy-ceramides||alpha-hydroxy fatty acids (AH)|
|esterified omega fatty acids (EOH)|
|saturated fatty acids (NH)|
|Phyto-ceramides||alpha-hydroxy fatty acids (AP)|
|esterified omega fatty acids (EOP)|
|saturated fatty acids (NP)|
|Free Fatty Acids||16:0, 16:1, 18:0, 18:1, 18:2, 20:0, 20:1,
20:2, 22:0, 22:1, 24:0, 24:1
|Sterols||Cholesterol, Cholesterol Sulfate|
SF-/MS/MS (Waters UPC2/Sciex QTrap 5500)
|Sample Type and Required Amounts|
|Sample Type||Sample Requirements|
|Stratum Corneum||4 D-Squame disks|
|Skin cell cultures||5 million cells|
Disclaimer: This method is for Research Use Only and is not to be used for diagnostic purposes.
Delivering Absolute Quantification for Research and Biomarker Analysis
Our readily available or custom developed quantitative assays help you achieve your research and biomarker validation objectives with precise and fully validated methods. Our targeted assays and panels cover >1,000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways, and physiological processes, and they can be customized to best fit any application.
Stratum Corneum Targeted Panel Applications
Personal Care & Cosmetics
Big Insights with Metabolon
Cited in over 3,000 publications, we help scientists and manufacturers gain greater insight into their studies through metabolomics. See how our approach can become a successful part of your workflow.
Related Metabolomics Resources
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617 Davis Drive, Suite 100
Morrisville, NC 27560
P.O. Box 110407
Research Triangle Park, NC 27709
+1 (919) 572-1711