Absolute quantification

Targeted Metabolomics

Gain precision insights into the presence, quantity, and significance of analytes for your research or diagnostic application.

  • 1,000+ Validated Analytes
  • Focused Analysis
  • Absolute Quantification

Speak to a Metabolomics Expert Today

Request a quote, get detailed information on sample types, or learn how metabolomics can accelerate your research.

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Absolute Quantification For Targeted Research

Metabolon offers targeted metabolomics services that deliver validated, quantitative data, designed to meet your unique research objectives.
With over 150 targeted methods providing absolute quantification of analytes, we have developed services that quantify more than 1,000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways, and physiological processes. Whether you’re conducting basic research or advancing clinical investigations, we are ready and able to support your study.

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Unravel Biological Systems

Precise and Quantitative Insights

Targeted metabolomics aims to analyze a specific set of metabolites within a biological sample, providing quantitative insights into metabolic processes. Unlike untargeted metabolomics, which explores a broad spectrum of metabolites, targeted metabolomics is designed to measure predefined metabolites of interest, making it ideal for studying particular metabolic pathways or biomarkers. This approach offers high sensitivity, specificity, and reproducibility, which makes it valuable for applications such as disease biomarker discovery, drug development, and understanding the molecular basis of health conditions.

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Impactful Discoveries

Targeted Data Acquisition For Actionable Insights

Metabolomics is a powerful tool for uncovering biological insights often missed by other research methods. From validating biomarkers and mapping metabolic pathways to understanding physiological responses, Metabolon’s targeted panels empower you to confirm hypotheses, be certain of your findings, and transform data into impactful discoveries. With cutting-edge technology and expert guidance, we help you achieve meaningful results—faster and with greater precision than other targeted services. 

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Validated Portfolio

Quantitative Assays For Broad Applications

Our method portfolio features over 150 validated targeted panels and assays designed to deliver robust, quantitative insights into small molecules. With more than 1,000 biochemicals analyzed across 20+ sample types, Metabolon equips you to study disease progression, evaluate environmental impacts, or fine-tune therapeutic strategies with unparalleled specificity and accuracy. 

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More Accurate Results

Advancements in Targeted Methods

Recent advancements in targeted metabolomics have significantly enhanced the precision and efficiency of metabolic analysis. Innovations in analytical techniques, such as improved mass spectrometry and chromatography technologies, have led to higher sensitivity and the ability to detect even trace levels of metabolites. Additionally, the development of more comprehensive and specialized metabolite databases has enabled the identification of a broader range of metabolites in complex biological samples. Advances in data analysis tools, including better quantification methods and software for interpreting large datasets, have further streamlined the process, allowing for faster, more accurate results.

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Absolute Quantification

Expertise in Endogenous Biomarkers

Metabolon’s expertise in measuring endogenous biomarkers—molecules naturally occurring within biological systems—is unparalleled. Unlike many bioanalytical services that focus on exogenous biomarkers, such as drugs or externally introduced compounds, our targeted panels are designed to quantify biomarkers intrinsic to the system being studied.

Because endogenous biomarkers often exist at the lower limits of analytical detection, assay sensitivity is critical. Even subtle changes in biomarker levels can carry significant biological implications. Metabolon’s highly sensitive and accurate targeted assays are specifically developed to detect and quantify these modest yet meaningful changes, providing precise and biologically relevant insights.

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Increased Flexibility

Key Benefits of Outsourcing Metabolomics

Outsourcing targeted metabolomics offers several advantages, including access to cutting-edge technology and expert knowledge without the need for significant investment in equipment or training. It helps reduce costs and speeds up the process, ensuring faster turnaround times and quicker insights. This flexibility allows for scalable solutions that can adapt to the needs of any project, large or small.

Key Questions to Ask Your Metabolomics Provider

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How Many Metabolites Can You Detect?

Targeted metabolomics requires a delicate balance between breadth of coverage and analytical precision. While a broad range of metabolites is essential to capture the complexity of biological systems, each targeted assay must maintain high accuracy, sensitivity, and reproducibility for reliable quantification. This balance is crucial for researchers to obtain comprehensive yet precise insights into specific metabolic pathways, disease states, or physiological processes.

Metabolon addresses this need by offering an extensive array of targeted metabolomics solutions that combine broad coverage with analytical rigor. Our targeted panels and assays encompass over 1000 metabolites and lipids, spanning diverse biochemical classes, metabolic pathways, and physiological processes. We provide disease-focused panels, pathway-specific assays, and analyte class-specific panels—such as our Inflammation Portfolio, Bile Acids Targeted Panel, and Complex Lipids Targeted Panel. By offering this range of targeted solutions, Metabolon enables researchers to achieve both the breadth and depth required for comprehensive metabolic investigations, while maintaining the high standards of accuracy and precision essential for targeted metabolomics.

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How Does Metabolon Support the Transition from Untargeted to Targeted Metabolomics?

A controlled and insightful research outcome is highly dependent on the quality of your study preparation. Every metabolomics study should begin with fully assessing your research goals and ensuring three main components are identifies: a clearly defined objective, strong study design elements, and adequate study power.

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What Metabolomics Technology Do You Use?

Two main technologies are used to obtain metabolite data: nuclear magnetic resonance (NMR) and liquid chromatography-mass spectrometry (LC-MS). The approach you use directly impacts your results.

Your Targeted Metabolomics Service Provider

Metabolon’s validated targeted panels and assays and custom method development services for absolute quantification of metabolites and lipids support wide-reaching research projects, enabling biomarker validation, diagnostic research, and routine basic research objectives.

We provide absolute quantification for more than 1,000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways, and physiological processes and can customize our methods to validate novel matrices to fit any application.

1,800,000+

Samples Analyzed

25

Years Experience

4,000+

Publications

45

Employees with PhDs

5,400+

Metabolites

15,000+

Completed Projects

Utility of Metabolomics

Explore how metabolomics has been used to advance research in your field of interest.

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Bioprocessing

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Blood Function & Disease

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Cardiology

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COVID-19

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Dermatology

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Diabetes

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Ecology

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Endocrinology

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Epidemiology

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Gastroenterology

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Hepatology

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Immune Function & Disease

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Immuno-Oncology

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Infectious Disease

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Inflammation

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Kidney Function & Disease

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Lung Function & Disease

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Microbiology

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Neuroscience

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Oncology

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Pediatrics

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Pharmacology & Toxicology

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Renal & Urological Disorders

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Respiratory Disorders

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Rheumatology

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Womens Health

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Bioprocessing

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Blood Function & Disease

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Cardiology

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COVID-19

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Dermatology

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Diabetes

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Ecology

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Endocrinology

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Epidemiology

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Gastroenterology

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Hepatology

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Immune Function & Disease

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Immuno-Oncology

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Infectious Disease

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Inflammation

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Kidney Function & Disease

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Lung Function & Disease

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Microbiology

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Neuroscience

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Oncology

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Pediatrics

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Pharmacology & Toxicology

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Renal & Urological Disorders

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Respiratory Disorders

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Rheumatology

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Womens Health

Our Targeted Panels & Single Analyte Assays

Learn more about our products and services to support targeted metabolomics analysis

Amino Acids Targeted Panel

Amino Acids Targeted Panel

Amino Acids Targeted Panel

Bile Acids Targeted Panel

Amino Acids Targeted Panel

Free Fatty Acids Targeted Panel

Amino Acids Targeted Panel

Short Chain Fatty Acids Targeted Panel

Amino Acids Targeted Panel

Central Carbons Targeted Panel

Amino Acids Targeted Panel

Insulin Resistance Targeted Panel

Amino Acids Targeted Panel

Metal Analysis Targeted Panel

Amino Acids Targeted Panel

Fatty Acids Metabolism Targeted Panel

Amino Acids Targeted Panel

Indoles/Uremic Toxicity Targeted Panel

Amino Acids Targeted Panel

Creatinine Single Analyte Assay

Amino Acids Targeted Panel

Oxysterols Targeted Panel

Amino Acids Targeted Panel

Salivary Glucose Single Analyte Assay

Amino Acids Targeted Panel

Sebum Targeted Panel

Amino Acids Targeted Panel

Stratum Corneum Targeted Panel

Amino Acids Targeted Panel

Tryptophan/Kynurenine Ratio Targeted Panel

Amino Acids Targeted Panel

C4 Single Analyte Assay

Amino Acids Targeted Panel

Beta Hydroxybutyrate Single Analyte Assay

icon quotes

“Metabolon has developed a solid, scalable solution to the non-trivial problem of metabolomics biochemical interpretation, specifically tailored to their world-leading data acquisition platform. Leveraging decades of experience in data curation, Metabolon provides intuitive visualization tools for pathway analysis and disease association, adding even more value to an already outstanding product.”

David Broadhurst, PhD
Professor of BioSystems Data Science at Edith Cowan University, Australia.

Featured Resources

Download our curated content below to learn more about untargeted metabolomics applications and creating a successful study. Find more in our comprehensive resource library here.

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eBrochure: Targeted Panels

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Why Metabolomics: Your Guide to Metabolomics

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Transitioning From Untargeted to Targeted Metabolomics

GET STARTED

Talk with an expert

Request a quote, get detailed information on sample types, or learn how metabolomics can accelerate your research. Find our contact details are here.

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References

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9. Fritsch, D.A., et al., Microbiome function underpins the efficacy of a fiber-supplemented dietary intervention in dogs with chronic large bowel diarrhea. BMC Vet Res, 2022. 18(1): p. 245.

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17. Maekawa, H., et al., SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress. J Clin Invest, 2025. 135(19).

18. Wu, D., et al., Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition. Gut, 2026.

19. Schwerdtfeger, L.A., et al., Gut microbiota and metabolites are linked to disease progression in multiple sclerosis. Cell Rep Med, 2025. 6(4): p. 102055.

20. Wu, H., et al., Microbiome-metabolome dynamics associated with impaired glucose control and responses to lifestyle changes. Nat Med, 2025. 31(7): p. 2222-2231.

21. Jacobs, J.P., et al., Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome, 2021. 9(1): p. 236.

22. Pietzner, M., et al., Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. Nat Med, 2021. 27(3): p. 471-479.

23. Faquih, T.O., et al., Robust Metabolomic Age Prediction Based on a Wide Selection of Metabolites. J Gerontol A Biol Sci Med Sci, 2025. 80(3).

24. Scherer, N., et al., Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits. Nat Genet, 2025. 57(1): p. 193-205.

25. Holmes, Z.C., et al., Untargeted metabolomic analysis of human milk from healthy mothers reveals drivers of metabolite variability. Sci Rep, 2024. 14(1): p. 20827.

26. Titz, B., et al., Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases. Transl Vis Sci Technol, 2024. 13(6): p. 17.

27. Bloom, S.M., et al., Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation. Nat Microbiol, 2022. 7(3): p. 434-450.

28. Leimer, E.M., et al., Lipid profile of human synovial fluid following intra-articular ankle fracture. J Orthop Res, 2017. 35(3): p. 657-666.