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Targeted Assays

Delivering Absolute Quantification for Research and Biomarker Analysis

Our readily available or custom developed quantitative assays help you achieve your research and biomarker validation objectives with precise and fully validated methods. Our targeted assays and panels cover >1000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways and physiological processes, and they can be customized to best fit any application.

Targeted Assays
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All Available Assays

  • 1,5-Anhydroglucitol
  • 7-alpha-Hydroxy-4-cholesten-3-one (C4)
  • Acylcarnitines
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Amino Acids
  • Beta-Hydroxybutyrate (3-Hydroxybutyric Acid)
  • Bile Acids
  • GCP Bile Acids
  • Biofluid Microbiome panel
  • Branched-Chain Amino Acids
  • Central Carbon Metabolism
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Creatinine
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Glucose
  • Histamine and Histidine
  • Impaired Glucose Tolerance Panel
  • Indoles/Uremic Toxicity
  • Insulin Resistance Panel
  • Malonyl Carnitine
  • Metal Cofactors and Toxic Metals
  • Neurotransmitters and Hormones
  • Oxylipins in Tissue
  • Polyamines
  • Purine Catabolism
  • Quantose®IGT Test (Impaired Glucose Tolerance)
  • Quantose®IR Test (Insulin Resistance)
  • Salivary Cortisol
  • Salivary HETE
  • Salivary p-Cresol Sulfate
  • Sebum Lipid Panel
  • Serotonin
  • Short Chain Fatty Acid Panel (SCFA)
  • GCP Short Chain Fatty Acid Panel (SCFA)
  • Sphingosine 1-Phosphate
  • Stratum Corneum Lipid Panel
  • Stress and Mood Hormones
  • Sulfated Bile Acid
  • Total Cholesterol
  • Total Triacylglycerides (TAGs)
  • Trimethylaminoxide (TMAO)
  • Tryptophan/Kynurenine
  • Urea Cycle
  • Urinary Catecholamines and Serotonin
  • Vancomycin
  • Vitamin D

Disease Related Metabolite Assays

Neuro Disorders
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Beta-Hydroxybutyrate (3-Hydroxybutyric Acid)
  • Bile Acids
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Glucose
  • Metal Cofactors and Toxic Metals
  • Neurotransmitters and Hormones
  • Polyamines
  • Purine Catabolism
  • Salivary Cortisol
  • Serotonin
  • Short Chain Fatty Acid Panel (SCFA)
  • Sphingosine 1-Phosphate
  • Stress and Mood Hormones
  • Sulfated Bile Acid
  • Total Cholesterol
  • Total Triacylglycerides (TAGs)
  • Trimethylaminoxide (TMAO)
  • Tryptophan/Kynurenine
  • Urinary Catecholamines and Serotonin
Metabolic Disorders
  • Acylcarnitines
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Amino Acids
  • Beta-Hydroxybutyrate (3-Hydroxybutyric Acid)
  • Branched-Chain Amino Acids
  • Central Carbon Metabolism
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Glucose
  • Impaired Glucose Tolerance Panel
  • Insulin Resistance Panel
  • Malonyl Carnitine
  • Metal Cofactors and Toxic Metals
  • Purine Catabolism
  • Quantose®IGT Test (Impaired Glucose Tolerance)
  • Quantose®IR Test (Insulin Resistance)
  • Sphingosine 1-Phosphate
  • Total Cholesterol
  • Total Triacylglycerides (TAGs)
  • Vitamin D
Myopathies & Mitochondrial Function
  • 7-alpha-Hydroxy-4-cholesten-3-one (C4)
  • Acylcarnitines
  • Amino Acids
  • Beta-Hydroxybutyrate (3-Hydroxybutyric Acid)
  • Bile Acids
  • Branched-Chain Amino Acids
  • Central Carbon Metabolism
  • Complex Lipid Panel
  • Creatinine
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Malonyl Carnitine
  • Purine Catabolism
  • Short Chain Fatty Acid Panel (SCFA)
  • Sphingosine 1-Phosphate
  • Sulfated Bile Acid
  • Trimethylaminoxide (TMAO)
  • Tryptophan/Kynurenine
  • Vitamin D
Immune System, Infectious Disease & COVID-19
  • Acylcarnitines
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Amino Acids
  • Beta-Hydroxybutyrate (3-Hydroxybutyric Acid)
  • Bile Acids
  • Central Carbon Metabolism
  • Cholesterol Metabolism
  • Fatty Acid Metabolism
  • Glucose
  • Histamine and Histidine
  • Indoles/Uremic Toxicity
  • Metal Cofactors and Toxic Metals
  • Oxylipins in Tissue
  • Polyamines
  • Salivary Cortisol
  • Salivary HETE
  • Serotonin
  • Short Chain Fatty Acid Panel (SCFA)
  • Sphingosine 1-Phosphate
  • Stress and Mood Hormones
  • Total Cholesterol
  • Trimethylaminoxide (TMAO)
  • Tryptophan/Kynurenine
  • Vitamin D
Cardiovascular Diseases
  • 7-alpha-Hydroxy-4-cholesten-3-one (C4)
  • Acylcarnitines
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Beta-Hydroxybutyrate (3-Hydroxybutyric Acid)
  • Biofluid Microbiome panel
  • Branched-Chain Amino Acids
  • Central Carbon Metabolism
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Glucose
  • Impaired Glucose Tolerance Panel
  • Insulin Resistance Panel
  • Metal Cofactors and Toxic Metals
  • Oxylipins in Tissue
  • Polyamines
  • Quantose®IGT Test (Impaired Glucose Tolerance)
  • Quantose®IR Test (Insulin Resistance)
  • Salivary HETE
  • Total Cholesterol
  • Total Triacylglycerides (TAGs)
  • Trimethylaminoxide (TMAO
Diabetes
  • 1,5-Anhydroglucitol
  • 7-alpha-Hydroxy-4-cholesten-3-one (C4)
  • Acylcarnitines
  • Amino Acids
  • Beta-Hydroxybutyrate (3-Hydroxybutyric Acid)
  • Bile Acids
  • Branched-Chain Amino Acids
  • Central Carbon Metabolism
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Creatinine
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Glucose
  • Impaired Glucose Tolerance Panel
  • Insulin Resistance Panel
  • Quantose®IGT Test (Impaired Glucose Tolerance)
  • Quantose®IR Test (Insulin Resistance)
  • Sulfated Bile Acid
  • Total Cholesterol
  • Total Triacylglycerides (TAGs)
  • Urea Cycle
Gut Health & Wellness
  • 7-alpha-Hydroxy-4-cholesten-3-one (C4)
  • Bile Acids
  • Biofluid Microbiome panel
  • Cholesterol Metabolism
  • Indoles/Uremic Toxicity
  • Oxylipins in Tissue
  • Salivary p-Cresol Sulfate
  • Serotonin
  • Short Chain Fatty Acid Panel (SCFA)
  • Sulfated Bile Acid
  • Trimethylaminoxide (TMAO)
  • Tryptophan/Kynurenine
  • Vancomycin
Health & Wellness
  • 1,5-Anhydroglucitol
  • Acylcarnitines
  • Amino Acids
  • Beta-Hydroxybutyrate (3-Hydroxybutyric Acid)
  • Biofluid Microbiome panel
  • Branched-Chain Amino Acids
  • Central Carbon Metabolism
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Creatinine
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Glucose
  • Impaired Glucose Tolerance Panel
  • Insulin Resistance Panel
  • Metal Cofactors and Toxic Metals
  • Neurotransmitters and Hormones
  • Quantose®IGT Test (Impaired Glucose Tolerance)
  • Quantose®IR Test (Insulin Resistance)
  • Salivary Cortisol
  • Serotonin
  • Stress and Mood Hormones
  • Total Cholesterol
  • Total Triacylglycerides (TAGs)
  • Urea Cycle
  • Urinary Catecholamines and Serotonin
  • Vitamin D
Cancer
  • Amino Acids
  • Bile Acids
  • Central Carbon Metabolism
  • Fatty Acid Metabolism
  • Glucose
  • Polyamines
  • Purine Catabolism
  • Sulfated Bile Acid
  • Trimethylaminoxide (TMAO)
  • Tryptophan/Kynurenine
Liver Diseases, NAFLD, NASH
  • 7-alpha-Hydroxy-4-cholesten-3-one (C4)
  • Acylcarnitines
  • Bile Acids
  • Branched-Chain Amino Acids
  • Central Carbon Metabolism
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Glucose
  • Insulin Resistance Panel
  • Quantose®IR Test (Insulin Resistance)
  • Sulfated Bile Acid
  • Total Cholesterol
  • Total Triacylglycerides (TAGs)
  • Urea Cycle
Kidney Function
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Biofluid Microbiome panel
  • Creatinine
  • Indoles/Uremic Toxicity
  • Polyamines
  • Salivary p-Cresol Sulfate
  • Trimethylaminoxide (TMAO)
  • Urea Cycle
Preeclampsia, Gestational Diabetes
  • 1,5-Anhydroglucitol
  • Amino Acids
  • Branched-Chain Amino Acids
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Creatinine
  • Fatty Acid Metabolism
  • Glucose
  • Purine Catabolism
  • Total Triacylglycerides (TAGs)
Endothelial Function
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Central Carbon Metabolism
  • Glucose
  • Histamine and Histidine
  • Metal Cofactors and Toxic Metals
  • Polyamines
  • Purine Catabolism
  • Sphingosine 1-Phosphate
  • Urea Cycle
Inflammation & Oxidative Stress
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Complex Lipid Panel
  • Fatty Acid Metabolism
  • Histamine and Histidine
  • Metal Cofactors and Toxic Metals
  • Oxylipins in Tissue
  • Polyamines
  • Purine Catabolism
  • Salivary Cortisol
  • Salivary HETE
  • Sphingosine 1-Phosphate
  • Tryptophan/Kynurenine
  • Urea Cycle
  • Vitamin D
Bone Health
  • Histamine and Histidine
  • Metal Cofactors and Toxic Metals
  • Polyamines
  • Salivary Cortisol
  • Serotonin
  • Sphingosine 1-Phosphate
  • Stress and Mood Hormones
  • Urinary Catecholamines and Serotonin
  • Vitamin D
Skin Health
  • Polyamines
  • Sebum Lipid Panel
  • Stratum Corneum Lipid Panel
  • Tryptophan/Kynurenine
  • Vitamin D
Aging
  • Acylcarnitines
  • Amino Acids
  • Central Carbon Metabolism
  • Cholesterol Metabolism
  • Complex Lipid Panel
  • Fatty Acid Metabolism
  • Free Fatty Acids
  • Glucose
  • Oxylipins in Tissue
  • Polyamines
  • Short Chain Fatty Acid Panel (SCFA)
  • Sphingosine 1-Phosphate
  • Total Cholesterol
  • Total Triacylglycerides (TAGs)
  • Trimethylaminoxide (TMAO)
Microbiome
  • 7-alpha-Hydroxy-4-cholesten-3-one (C4)
  • Bile Acids
  • Biofluid Microbiome panel
  • Cholesterol Metabolism
  • Histamine and Histidine
  • Indoles/Uremic Toxicity
  • Oxylipins in Tissue
  • Salivary p-Cresol Sulfate
  • Serotonin
  • Short Chain Fatty Acid Panel (SCFA)
  • Sulfated Bile Acid
  • Trimethylaminoxide (TMAO)
  • Tryptophan/Kynurenine
  • Vancomycin
Safety & Toxicology
  • ADMA/SDMA (Nitric Oxide Pathway)
  • Bile Acids
  • Creatinine
  • Oxylipins in Tissue
  • Polyamines
  • Purine Catabolism
  • Sulfated Bile Acid
  • Tryptophan/Kynurenine
  • Urea Cycle
Laboratory Developed Test
  • Quantose®IGT Test (Impaired Glucose Tolerance)
  • Quantose®IR Test (Insulin Resistance)

Don’t you see your metabolite or biomarker of interest?

Contact us for inquiries on developing your custom targeted assay to fit any requirement from research-use-only to good clinical practice (GCP) in compliance with FDA guidelines.

Request Information

Targeted Assays from Metabolon

Talk With an Expert About Custom Assays
Core of Biomarker Development Program
Informing the entire drug discovery & development cycle

Targeted assays are a valuable tool for rapidly and accurately establishing pharmacodynamics, translational studies, gauging efficacy and safety, and post-market surveillance studies. With several different sample matrices supported, deeper insights can be gained in various applications including microbiome research and bioprocessing.

Core of biomarker development

From discovery to commercialization, improve biological understanding by tracking biomarkers with targeted metabolite assays. The role of biomarkers is expanding to inform new indications and targets, patient segmentation and novel mechanisms of action. According to the context of use of your biomarkers, Metabolon can guide you to ensure study integrity and high quality data generation in compliance with regulatory standards.

Custom assay development

If one of our existing targeted assay panels doesn’t meet your needs, our experienced team of scientist can create a custom assay specifically for your area of interest. We have developed 150 customized assays representing >300 metabolites from all areas of the metabolome with multiplexing support. All of our assays are backed by our validations for Research use only (RUO) or GCP/GCLP and CLIA.

Research Purposes
  • Readily Available Quantitative Metabolite Assays or Custom Assay Development according to ISO 9001:2015 standards
Phase I, II, III Clinical Studies
  • Fit-For-Purpose Biomarker Validation
  • Capability to adhere to Good Clinical Practice (GCP)/ Good Clinical Laboratory Practice (GCLP) standards
  • Extensive Method Validation according to FDA Bioanalytical Method Validation Guidance, 2018 or EMA Guideline on Bioanalytical Method Validation, 2011
Clinical Diagnostics
  • Capability to develop/validate methods and perform diagnostic testing on human samples according regulations certified by Clinical Laboratory Improvement Amendments (CLIA) and accredited by the College of American Pathologists (CAP) for diagnostic testing on human samples

Expert Consultation

Guide Your Biomarker Development

Start your project or request more information

Targeted Assay Expert

Each project begins with a scientist-to-scientist consultation to determine your assay needs, including regulatory requirements and project timeline. In doing so, we explore how to best meet those needs through existing assays, custom-developed assays, or a combination of both.

Related Resources

See All Resources
eBrochure: Targeted Assays – Delivering Absolute Quantification for Research and Biomarker Analysis

eBrochure: Targeted Assays – Delivering Absolute Quantification for Research and Biomarker Analysis

Finding Success with Metabolon: How Pharma Companies Utilize Metabolomics to Advance Therapies

Finding Success with Metabolon: How Pharma Companies Utilize Metabolomics to Advance Therapies

How United Therapeutics leverages metabolomics to get closer to the phenotype increasing confidence in clinical trial decisions

How United Therapeutics leverages metabolomics to get closer to the phenotype increasing confidence in clinical trial decisions

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Enlighten your research,
accelerate your discovery.

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or Talk With an Expert

Metabolomics

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  • Technology & Knowledgebase
  • Quality Assurance
  • Setting the Standard: The 4Cs
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