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SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress

Author: Maekawa, Hiroshi; Zhou, Yalu; Aoi, Yuki; Fain, Margaret E.; Kaminski, Dorian S.; Kong, Hyewon; Sebo, Zachary L.; Chakrabarty, Ram P.; Howard, Benjamin C.; Andersen, Grant; Marcheva, Biliana; Gao, Peng; Kapitsinou, Pinelopi; Bass, Joseph; Shilatifard, Ali; Chandel, Navdeep S.; Quaggin, Susan E.
Year Published: 2025
Media Outlet: Journal of Clinical Investigation

Open Access? No

Matrix: Plasma and Serum
Biological Themes: Kidney function
Product(s): Global Discovery Panel
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