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Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy

Author: Klebanoff, Christopher A.; Crompton, Joseph G.; Leonardi, Anthony J.; Yamamoto, Tori N.; Chandran, Smita S.; Eil, Robert L.; Sukumar, Madhusudhanan; Vodnala, Suman K.; Hu, Jinhui; Ji, Yun; Clever, David; Black, Mary A.; Gurusamy, Devikala; Kruhlak, Michael J.; Jin, Ping; Stroncek, David F.; Gattinoni, Luca; Feldman, Steven A.; Restifo, Nicholas P.
Year Published: 2017
Media Outlet: JCI Insight

Open Access? No

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