One kit, broad applications

The Metabolon Verus™ Kit enables breakthrough research across therapeutic areas, research settings, and sample types.

IBP on a computer with kits reagents

One kit, broad applications

The Metabolon Verus™ Kit enables breakthrough research across therapeutic areas, research settings, and sample types.

IBP on a computer with kits reagents

Explore themes and applications

For the Metabolon Verus™ Metabolomics Profiling Kit

Applications
Biological Themes

Biomarker Studies

Disease
Treatment response

Identify metabolite signatures associated with disease, treatment response, or physiological states to support biomarker discovery and validation.

Multi-omics Integration

Genomics
Transcriptomics
Proteomics

Integrate metabolomics with genomics, transcriptomics, proteomics, and microbiome data to connect molecular changes to real-time biological phenotype.

Mechanism of Action

Drugs
Interventions
Exposures

Reveal pathway perturbations and biochemical responses that help explain how drugs, interventions, or environmental exposures impact biology.

Drug Target Discovery

Connected pathways
Biological processes

Identify metabolically connected pathways and biological processes that uncover novel therapeutic
targets and opportunities for intervention.

Disease Underpinnings

Disease progression
Molecular mechanisms

Characterize altered metabolic pathways to better understand disease biology, progression, and underlying molecular mechanisms.

Patient Stratification

Precision medicine
Cohort definition

Differentiate patient subgroups based on metabolic phenotypes to support precision medicine and improved cohort definition.

Responder/Non-Responder

Therapeutic response
Treatment outcomes

Identify metabolic patterns associated with therapeutic response or resistance to help predict and monitor treatment outcomes.

Population Studies

Population health

Enable large-scale characterization of metabolic variation across populations to study health, disease
risk, lifestyle, diet, and environmental influences.

Safety/Toxicity Assessment

Toxicity
Organ stress

Detect biochemical changes associated with toxicity, organ stress, or off-target effects to support safety evaluation and risk assessment.

Biological Stress

Oxidative stress
Redox

Profile markers that report on systemic biological stress responses such as inflammation, injury, glycemic stress, oxidative stress, wasting and stress signaling molecules.

Exposome and Nutrition

Diet response
Xenobiotics

Profile a variety of exposures including dietary, halogens, consumer products and medications.

Microbiome Research

Gut dysbiosis
Bile acids

Measure microbial signals that influence human health through secondary bile acids, aromatic / indole amino acid derivatives and many other metabolites of established microbial origin.

Liver Function

Phase 2 metabolism

See functional outputs of liver Phase 2 metabolism, as well as markers that report on liver health.

Kidney Function

Uremic toxins

See metabolites that report on kidney function and injury, as well as uremic toxins.

Energy and Mitochondrial Health

TCA cycle
Mitochondria

Profile metabolites from central energy pathways, as well as cofactors that support reactions, signaling molecules and molecules catabolized to generate energy.

Cancer Metabolism

Glycolysis
Redox balance

Characterize tumor-driven metabolic reprogramming through alterations in glycolysis, TCA cycle intermediates, amino acid utilization, redox balance, and oncometabolite pathways associated with proliferation and therapeutic response.

Metabolic Disease

Insulin resistance
Cardiometabolism

Profile lipid metabolism, bile acid signaling, acylcarnitines, and amino acid pathways linked to insulin resistance, mitochondrial dysfunction, cardiometabolic health, and energy homeostasis.

Immunometabolism

Inflammation
Immune profiling

Characterize tryptophan/arginine pathways and lipid mediators that define immune tone and inflammatory state.

Explore themes and applications for the Metabolon Verus™ Metabolomics Profiling Kit

Applications
Biological Themes

Biomarker Studies

Disease
Treatment response

Identify metabolite signatures associated with disease, treatment response, or physiological states to support biomarker discovery and validation.

Multi-omics Integration

Genomics
Transcriptomics
Proteomics

Integrate metabolomics with genomics, transcriptomics, proteomics, and microbiome data to connect molecular changes to real-time biological phenotype.

Mechanism of Action

Drugs
Interventions
Exposures

Reveal pathway perturbations and biochemical responses that help explain how drugs, interventions, or environmental exposures impact biology.

Drug Target Discovery

Connected pathways
Biological processes

Identify metabolically connected pathways and biological processes that uncover novel therapeutic
targets and opportunities for intervention.

Disease Underpinnings

Disease progression
Molecular mechanisms

Characterize altered metabolic pathways to better understand disease biology, progression, and underlying molecular mechanisms.

Patient Stratification

Precision medicine
Cohort definition

Differentiate patient subgroups based on metabolic phenotypes to support precision medicine and improved cohort definition.

Responder/Non-Responder

Therapeutic response
Treatment outcomes

Identify metabolic patterns associated with therapeutic response or resistance to help predict and monitor treatment outcomes.

Population Studies

Population health

Enable large-scale characterization of metabolic variation across populations to study health, disease
risk, lifestyle, diet, and environmental influences.

Safety/Toxicity Assessment

Toxicity
Organ stress

Detect biochemical changes associated with toxicity, organ stress, or off-target effects to support safety evaluation and risk assessment.

Biological Stress

Oxidative stress
Redox

Profile markers that report on systemic biological stress responses such as inflammation, injury, glycemic stress, oxidative stress, wasting and stress signaling molecules.

Exposome and Nutrition

Diet response
Xenobiotics

Profile a variety of exposures including dietary, halogens, consumer products and medications.

Microbiome Research

Gut dysbiosis
Bile acids

Measure microbial signals that influence human health through secondary bile acids, aromatic / indole amino acid derivatives and many other metabolites of established microbial origin.

Liver Function

Phase 2 metabolism

See functional outputs of liver Phase 2 metabolism, as well as markers that report on liver health.

Kidney Function

Uremic toxins

See metabolites that report on kidney function and injury, as well as uremic toxins.

Energy and Mitochondrial Health

TCA cycle
Mitochondria

Profile metabolites from central energy pathways, as well as cofactors that support reactions, signaling molecules and molecules catabolized to generate energy.

Cancer Metabolism

Glycolysis
Redox balance

Characterize tumor-driven metabolic reprogramming through alterations in glycolysis, TCA cycle intermediates, amino acid utilization, redox balance, and oncometabolite pathways associated with proliferation and therapeutic response.

Metabolic Disease

Insulin resistance
Cardiometabolism

Profile lipid metabolism, bile acid signaling, acylcarnitines, and amino acid pathways linked to insulin resistance, mitochondrial dysfunction, cardiometabolic health, and energy homeostasis.

Immunometabolism

Inflammation
Immune profiling

Characterize tryptophan/arginine pathways and lipid mediators that define immune tone and inflammatory state.

See the Metabolon Verus™ Kit in action for your application

See the Metabolon Verus™ Kit in action for your application

Instrument Requirements

LC platform Waters Acquity I-Class UPLC
Thermo Vanquish Flex or Horizon
Mass spec platform Thermo Scientific Orbitraps
  • Tribrids (IDX/IQX)
  • Orbitrap Exploris series (120/240/480)
  • Q Exactive (Plus and UHMR)
More instruments to follow
Software required Xcalibur 4.2 or higher Freestyle 1.8 or higher Tune Software 2.11 or higher
Column (not included) Waters BEH C18 (2.1 × 100 mm, 1.7 µm) column is required for this kit (not included)

Register your interest

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