Exploratory Panels

Metabolon Target

Exploratory Panels

R Any Panel

R Any Matrix

R Any Study

Panels

20+

Analytes

450+

Matrices

40+

About Exploratory Panels

Absolute quantification of any analyte, in any sample, anytime—All Metabolon Target targeted panels and assays are available to purchase as Exploratory Panels.

An Exploratory Panel allows customers to leverage Metabolon’s expertly developed and validated methods in any exploratory matrix, giving you immediate access to high-quality, rigorously tested, optimized, and calibrated methodology as the foundations for your study using any sample type.

Explore Functional Phenotype In Any Biological Sample

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Plant Matrices
Alfalfa Algae Alligator Wood Allium
Apple Arabidopsis Blueberry Brassica
Cacao Camelina Corn Cotton
Cranberry Cucumber Euphoria Ginseng
Hibiscus Hydrangea Iceplant Kalanchoe
Maize Millet Moss Oat
Opuntia (Cactus) Orange Oryza Sativa (Rice) Palm
Pea Peanut Peony Pepper
Petunia Pine Pomegranate Poplar
Potato Pumpkin Selaginella Sorphum
Soybean Sporobolus Sugar Beet Sugarcane
Summergrass Switchgrass Teff Tobacco
Tomato Walnut Watermelon Wheat
Human Matrices
Adrenal Gland Amniotic Fluid Aqueous Humor Ascites
BALF Bile Bone Marrow Breast Milk
Breath Condensate Cartilage Colon Dried Blood Spots
Endometrium Fallopian Tube Feces Hair Follicles
Heart Illeum Kidney Liver
Muscle Ovary Plasma Prostate
Retina Saliva Sebum Serum
Skin Spleen Sweat Synovial Fluid
Tears Tumor Urine Urine Sediment
Vitreous Fluid Whole Blood
Animal Matrices
Cat Chicken Cow Dog
Dolphin Ferret Fish (various) Fox
Frog Goat Guinea Pig Hamster
Horse Insect (various) Lobster Mollusk (various)
Monkey Mouse Nematode Pig
Rabbit Rat Reptile (various) Sea Urchin
Sheep Squirrel
Other Matrices
Cell Media Fungus (Yeast) Hydrolysates Mammalian Cells (CHO, HELA, Lymphocytes, RBC, etc.)
Non-Mammalian Cells (Bacteria, etc.) Organoids Phytoplankton

Validating the Non-Validated

While unlikely, using a validated methodology with a non-validated matrix may inflate the signal-to-noise ratio (SNR), complicating the analysis of your samples. To ensure the data we collect for your study is accurate and meets Metabolon’s quality standards for all validated Metabolon Target panels, we may ask you to first participate in an initial pilot study. This will give you an early indication of the ability of the combination of our panel and your chosen matrix to potentially detect, identify, and quantify biomarkers, allowing us to proceed with your full study with confidence.

Sample Matrix Validation Services

We partner with businesses and institutions to develop targeted metabolomics services for all research areas and commercial objectives. If your study relies on a specific matrix or a unique set of analytes, inquire about our Sample Matrix Validation or Custom Method Development services. Any validation or development request will be tailored to your needs and ensure the highest possible accuracy, quality, and reproducibility for your current and future projects.

Delivering Absolute Quantification for Research and Biomarker Analysis

Our readily available or custom developed quantitative assays help you achieve your research and biomarker validation objectives with precise and fully validated methods. Our targeted assays and panels cover >1,000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways, and physiological processes, and they can be customized to best fit any application.

Sample Matrix Validation Details

Our Quality—ISO 9001:2015 Certified Laboratory

Metabolon offers three levels of sample validation: Exploratory (research-oriented, limited validation), RUO (Routine Use Only), and GCP/GCLP (Good Clinical Practice / Good Clinical Laboratory Practice).

All methods at Metabolon are validated to adhere to Metabolon’s ISO 9001:2015 certified quality system. Validation experiments are based on the FDA, EMA, and ICH M10 Bioanalytical Guidance documents. All data are peer-reviewed, and a summary report containing the results of the validation experiment is provided.

For GCP/GCLP validation, all experiments and acceptance criteria strictly adhere to the FDA, EMA, and ICH M10 Bioanalytical Guidances. All GCP/GCLP studies are peer-reviewed and audited by the Metabolon Quality Assurance Department. A validation report containing all of the elements listed in the M10 Bioanalytical Guidance is provided.

The table below outlines all evaluated analytical performance parameters for Exploratory, RUO, and GCP/GCLP standards.

ISO 9001

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Method Validation Offerings
Evaluated Parameters Exploratory RUO GCP/GCLP
Linearity, Accuracy, and Precision of Calibration Standards ✓ (1 run) (3 runs) (3 runs)
QC Precision Accuracy ✓ (3 levels) ✓ (3 levels)
Lower Limit of Quantitation ✓ (1 run) ✓ (3 runs) ✓ (3 runs)
Selectivity ✓ (1 run) ✓ (3 runs) ✓ (3 runs)
Carryover ✓ (1 run) ✓ (3 runs) ✓ (3 runs)
Dilution Accuracy
Extraction Recovery (also used to show accuracy)
Sample Stability Testing – Benchtop Stability
Sample Stability Testing – Freeze/Thaw Stability
Secondary Instrument
Parallelism
Matrix Effect Testing
Specificity
Sample Stability Testing – Long-Term Stability
Extract Stability Testing
Run Injection Stability Testing
Solution Stability Testing
QA Review

Big Insights with Metabolon

Cited in over 3,000 publications, we help scientists and manufacturers gain greater insight into their studies through metabolomics. See how our approach can become a successful part of your workflow.

Contact Us

Talk with an expert

Request a quote for our services, get more information on sample types and handling procedures, request a letter of support, or submit a question about how metabolomics can advance your research.

Corporate Headquarters

617 Davis Drive, Suite 100
Morrisville, NC 27560

Mailing Address:
P.O. Box 110407
Research Triangle Park, NC 27709

+1 (919) 572-1711

+1 (919) 572-1721

References

1. Zgoda-Pols, J.R., et al., Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: investigation of nicotinic acid receptor agonists. Toxicol Appl Pharmacol, 2011. 255(1): p. 48-56.

2. Bryant, J.A., et al., The impact of an oral purified microbiome therapeutic on the gastrointestinal microbiome. Nat Med, 2026. 32(1): p. 186-196

3. McGovern, B .H., et al., SER-109, an Investigational Microbiome Drugto Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial. Clin Infect Dis, 2021. 72(12): p. 2132-2140.

4. Feuerstadt, P., et al., SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection. N Engl J Med, 2022. 386(3): p. 220-229.

5. Hu, Z., et al., Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer. Mol Oncol, 2025. 19(6): p. 1737-1750.

6. Butler, F.M., et al., Vegetarian Dietary Patterns and Diet-Related Metabolites Are Associated With Kidney Function in the Adventist Health Study-2 Cohort. J Ren Nutr, 2025.

7. Stanford, J., et al., Metabolomic Profiling and Diet Quality Scoring in a Randomized Crossover Trial of Healthy and Typical Dietary Patterns. Mol Nutr Food Res, 2025 . 69(23): p. e70271.

8. O’Connor, L.E., et al., Metabolomic Profiling of an Ultraprocessed Dietary Pattern in a Domiciled Randomized Controlled Crossover Feeding Trial. J Nutr, 2023. 153(8): p. 2181-2192.

9. Fritsch, D.A., et al., Microbiome function underpins the efficacy of a fiber-supplemented dietary intervention in dogs with chronic large bowel diarrhea. BMC Vet Res, 2022. 18(1): p. 245.

10. Leal, L.N., et al., Preweaning nutrient supply improves lactation productivity and reduces the risk of culling in Holstein cows. J Dairy Sci, 2025. 108(6): p. 5875-5888.

11. Ahsin, M., et al., Soil and pasture health underlie improved beef nutrient density determined by untargeted metabolomics in Southern US grass finished beef systems. NPJ Sci Food, 2025. 9(1): p. 151.

12. Yin, W., et al., Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia. J Lipid Res, 2012. 53(1): p. 51-65.

13. Porter, F .D., et al., Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease. Sci Transl Med, 2010. 2(56): p. 56ra81.

14. Needham, B .D., et al., Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder. Biol Psychiatry, 2021. 89(5): p. 451-462

15. Li, C., et al., Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells. J Exp Med, 2014. 211(1): p. 15-28.

16. Green, P.G., et al., Metabolic flexibility and reverse remodelling of the failing human heart. Eur Heart J, 2025. 46(25): p. 2422-2433.

17. Maekawa, H., et al., SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress. J Clin Invest, 2025. 135(19).

18. Wu, D., et al., Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition. Gut, 2026.

19. Schwerdtfeger, L.A., et al., Gut microbiota and metabolites are linked to disease progression in multiple sclerosis. Cell Rep Med, 2025. 6(4): p. 102055.

20. Wu, H., et al., Microbiome-metabolome dynamics associated with impaired glucose control and responses to lifestyle changes. Nat Med, 2025. 31(7): p. 2222-2231.

21. Jacobs, J.P., et al., Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome, 2021. 9(1): p. 236.

22. Pietzner, M., et al., Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. Nat Med, 2021. 27(3): p. 471-479.

23. Faquih, T.O., et al., Robust Metabolomic Age Prediction Based on a Wide Selection of Metabolites. J Gerontol A Biol Sci Med Sci, 2025. 80(3).

24. Scherer, N., et al., Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits. Nat Genet, 2025. 57(1): p. 193-205.

25. Holmes, Z.C., et al., Untargeted metabolomic analysis of human milk from healthy mothers reveals drivers of metabolite variability. Sci Rep, 2024. 14(1): p. 20827.

26. Titz, B., et al., Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases. Transl Vis Sci Technol, 2024. 13(6): p. 17.

27. Bloom, S.M., et al., Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation. Nat Microbiol, 2022. 7(3): p. 434-450.

28. Leimer, E.M., et al., Lipid profile of human synovial fluid following intra-articular ankle fracture. J Orthop Res, 2017. 35(3): p. 657-666.