Panels
Analytes
Matrices
Absolute quantification of any analyte, in any sample, anytime—All Metabolon Target targeted panels and assays are available to purchase as Exploratory Panels.
An Exploratory Panel allows customers to leverage Metabolon’s expertly developed and validated methods in any exploratory matrix, giving you immediate access to high-quality, rigorously tested, optimized, and calibrated methodology as the foundations for your study using any sample type.
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| Plant Matrices | |||
|---|---|---|---|
| Alfalfa | Algae | Alligator Wood | Allium |
| Apple | Arabidopsis | Blueberry | Brassica |
| Cacao | Camelina | Corn | Cotton |
| Cranberry | Cucumber | Euphoria | Ginseng |
| Hibiscus | Hydrangea | Iceplant | Kalanchoe |
| Maize | Millet | Moss | Oat |
| Opuntia (Cactus) | Orange | Oryza Sativa (Rice) | Palm |
| Pea | Peanut | Peony | Pepper |
| Petunia | Pine | Pomegranate | Poplar |
| Potato | Pumpkin | Selaginella | Sorphum |
| Soybean | Sporobolus | Sugar Beet | Sugarcane |
| Summergrass | Switchgrass | Teff | Tobacco |
| Tomato | Walnut | Watermelon | Wheat |
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| Human Matrices | |||
|---|---|---|---|
| Adrenal Gland | Amniotic Fluid | Aqueous Humor | Ascites |
| BALF | Bile | Bone Marrow | Breast Milk |
| Breath Condensate | Cartilage | Colon | Dried Blood Spots |
| Endometrium | Fallopian Tube | Feces | Hair Follicles |
| Heart | Illeum | Kidney | Liver |
| Muscle | Ovary | Plasma | Prostate |
| Retina | Saliva | Sebum | Serum |
| Skin | Spleen | Sweat | Synovial Fluid |
| Tears | Tumor | Urine | Urine Sediment |
| Vitreous Fluid | Whole Blood | ||
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| Animal Matrices | |||
|---|---|---|---|
| Cat | Chicken | Cow | Dog |
| Dolphin | Ferret | Fish (various) | Fox |
| Frog | Goat | Guinea Pig | Hamster |
| Horse | Insect (various) | Lobster | Mollusk (various) |
| Monkey | Mouse | Nematode | Pig |
| Rabbit | Rat | Reptile (various) | Sea Urchin |
| Sheep | Squirrel | ||
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| Other Matrices | |||
|---|---|---|---|
| Cell Media | Fungus (Yeast) | Hydrolysates | Mammalian Cells (CHO, HELA, Lymphocytes, RBC, etc.) |
| Non-Mammalian Cells (Bacteria, etc.) | Organoids | Phytoplankton | |
Our readily available or custom developed quantitative assays help you achieve your research and biomarker validation objectives with precise and fully validated methods. Our targeted assays and panels cover more than 1,000 metabolites and lipids across a wide range of biochemical classes, metabolic pathways, and physiological processes, and they can be customized to best fit any application.
Metabolon offers three levels of sample validation: Exploratory (research-oriented, limited validation), RUO (Routine Use Only), and GCP/GCLP (Good Clinical Practice / Good Clinical Laboratory Practice).
All methods at Metabolon are validated to adhere to Metabolon’s ISO 9001:2015 certified quality system. Validation experiments are based on the FDA, EMA, and ICH M10 Bioanalytical Guidance documents. All data are peer-reviewed, and a summary report containing the results of the validation experiment is provided.
For GCP/GCLP validation, all experiments and acceptance criteria strictly adhere to the FDA, EMA, and ICH M10 Bioanalytical Guidances. All GCP/GCLP studies are peer-reviewed and audited by the Metabolon Quality Assurance Department. A validation report containing all of the elements listed in the M10 Bioanalytical Guidance is provided.
The table below outlines all evaluated analytical performance parameters for Exploratory, RUO, and GCP/GCLP standards.
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| Evaluated Parameters | Exploratory | RUO | GCP/GCLP |
|---|---|---|---|
| Linearity, Accuracy, and Precision of Calibration Standards | ✓ (1 run) | ✓ (3 runs) | ✓ (3 runs) |
| QC Precision Accuracy | ✓ (1 level, precision only) | ✓ (3 levels) | ✓ (3 levels) |
| Lower Limit of Quantitation | ✓ (1 run) | ✓ (3 runs) | ✓ (3 runs) |
| Selectivity | ✓ (1 run) | ✓ (3 runs) | ✓ (3 runs) |
| Carryover | ✓ (1 run) | ✓ (3 runs) | ✓ (3 runs) |
| Dilution Accuracy | ✕ | ✓ | ✓ |
| Extraction Recovery (also used to show accuracy) | ✕ | ✓ | ✓ |
| Sample Stability Testing – Benchtop Stability | ✕ | ✓ | ✓ |
| Sample Stability Testing – Freeze/Thaw Stability | ✕ | ✓ | ✓ |
| Secondary Instrument | ✕ | ✕ | ✓ |
| Parallelism | ✕ | ✕ | ✓ |
| Matrix Effect Testing | ✕ | ✕ | ✓ |
| Specificity | ✕ | ✕ | ✓ |
| Sample Stability Testing – Long-Term Stability | ✕ | ✕ | ✓ |
| Extract Stability Testing | ✕ | ✕ | ✓ |
| Run Injection Stability Testing | ✕ | ✕ | ✓ |
| Solution Stability Testing | ✕ | ✕ | ✓ |
| QA Review | ✕ | ✕ | ✓ |
While unlikely, using a validated methodology with a non-validated matrix may inflate the signal-to-noise ratio (SNR), complicating the analysis of your samples. To ensure the data we collect for your study is accurate and meets Metabolon’s quality standards for all validated Metabolon Target panels, we may ask you to first participate in an initial pilot study. This will give you an early indication of the ability of the combination of our panel and your chosen matrix to potentially detect, identify, and quantify biomarkers, allowing us to proceed with your full study with confidence.
We partner with businesses and institutions to develop targeted metabolomics services for all research areas and commercial objectives. If your study relies on a specific matrix or a unique set of analytes, inquire about our Sample Matrix Validation or Custom Method Development services. Any validation or development request will be tailored to your needs and ensure the highest possible accuracy, quality, and reproducibility for your current and future projects.
Once you see the full value of metabolomics, the only remaining question is: who does it best? While many laboratories have metabolite profiling or analytical chemistry capabilities, comprehensive metabolomics technologies are extremely rare.
Accurate, unbiased metabolite identification across the entire metabolome introduces signal-to-noise challenges that very few labs are equipped to handle. Also, translating massive quantities of data into actionable information is slow, if not impossible, for most because proper interpretation takes two things that are in short supply: experience and a comprehensive database.
Using our robust platform and visualization tools, our experts are uniquely able to tell you more about your molecule and develop assay panels to help you zero in on the results you need.
Coverage
Ability to interrogate thousands of metabolites across diverse biochemical space, revealing new insights and opportunities
Comparability
Ability to integrate the data from different studies into the same dataset, in different geographies, among different patients over time
Competency
Ability to inform on proper study design, generate high‐quality data, derive biological insights, and make actionable recommendations
Capacity
Ability to process hundreds of thousands of samples quickly and cost‐efficiently to service rapidly growing demand
