Metabolomics and Microbiome Research

Various species of bacteria colonize the human gut. Known as the microbiome, this collection of microbes is remarkably diverse, even among healthy individuals. The metabolic significance of this (in)human organ is now recognized, as microbial metabolites are known to influence immune function, metabolism, cardiovascular health, cognition, behavior, nutrient acquisition from food, and even a person’s response to therapeutics such as chemotherapy. The wide range of metabolites produced by the microbiomes in our gut represents a wealth of potential biomarkers and therapeutic targets. Therefore, it is no longer enough to determine “who is there” but rather “what are they doing?”