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Metabolon Announces a Quarter Century of Scientific Innovation, Industry Leadership, and Transformative Contributions to Life Science

A recognized pioneer in metabolomics, Metabolon is the most experienced and trusted metabolomics partner in the life sciences industry

MORRISVILLE, N.C. – July 8, 2025 – Metabolon, Inc., the global leader in providing metabolomics solutions advancing a wide variety of life science research, diagnostic, therapeutic development, and precision medicine applications, proudly announces its 25th anniversary—a milestone that marks a quarter-century of scientific innovation and transformative contributions to health, wellness, and life sciences through the power of metabolomics.

Founded in 2000, Metabolon pioneered the field of metabolomics by unlocking the potential of small molecules to drive breakthrough discoveries across clinical research, drug development, precision medicine, and beyond.  Today, Metabolon is the industry’s leading metabolomics service provider with over 25 years of experience delivering high-quality data and actionable insights to researchers worldwide.  Metabolon continues to push the boundaries of scientific innovation with integrated bioinformatics tools and ground-breaking metabolomics services – no other metabolomics provider has as many workflow patents as Metabolon. 

Why is Metabolon the industry’s best-in-class metabolomics service provider?

  • Extensive Scientific Track Record: Metabolon has contributed to over 4,000 peer-reviewed publications, making Metabolon the most-published metabolomics service provider globally.  These scientific publications include high-impact studies across oncology, neuroscience, immunology, cardiometabolic disease, and beyond.  Since its founding, Metabolon has completed over 15,000 customer projects and processed more than 1.8 million samples.
  • Industry Gold Standard: Metabolon’s platform combines ultra-high-performance liquid chromatography / tandem accurate mass spectrometry (UHPLC/MS/MS) with the world’s most extensive proprietary biochemical reference library that contains over 5,400 metabolites spanning 85+ metabolic pathways. 

    Our platform supports the world’s leading population health research initiatives, including CLSA (Canadian Longitudinal Study of Aging), EPIC (European Prospective Investigation into Cancer) Norfolk Study, FinnGen, Genomics England Ltd., HELIOS (Health for Life in Singapore), IMPACC (ImmunoPhenotyping Assessment in a COVID-19 Cohort), MVP (Million Veteran Program), TOPMed (Trans-Omics for Precision Medicine), TwinsUK (UK Adult Twin Registry), and others, to drive discoveries with the potential to translate into improved clinical outcomes, health equity, and precision interventions.  As the global industry standard, Metabolon’s services allow for broad scientific collaboration and support data and research longevity.
  • Unrivaled Data Quality: Metabolon projects are backed by rigorous QC protocols, ISO 9001:2015 certification, CLIA and CAP certifications, and robust standard operating procedures, ensuring data reproducibility and consistency across thousands of studies globally.  No other metabolomics vendor carries as many certifications or quality control measures.
  • Trusted by Leading Organizations: Metabolon serves thousands of clients worldwide, including the majority of the top pharmaceutical, biotechnology, and academic institutions.  Metabolon empowers these organizations to shorten development timelines, accelerate pipeline progression, and support evidence-based decisions for clinical asset optimization.

“Reaching our 25th anniversary is a tremendous honor and a testament to the passion and expertise of our global team and partners,” said Rohan Hastie, Ph.D., President and CEO of Metabolon.  “From the start, our mission has been to decode the biological language of metabolites to transform science and medicine.  We’re proud of what we’ve achieved and excited for what’s ahead as we continue shaping the future of health through metabolomics.”

To learn more about Metabolon’s Global Discovery Panel, please visit:
https://www.metabolon.com/services/untargeted-metabolomics/global-panel/

About Metabolon 
Metabolon, Inc. is the global leader in metabolomics, with a mission to deliver biochemical data and insights that expand and accelerate the impact of life sciences research and complement other ‘omics’ technologies.  With 25 years of experience, 15,000+ client projects, 4,000+ scientific publication references, and ISO 9001:2015, CLIA, and CAP certifications, Metabolon has developed industry-leading scientific, technology, and bioinformatics techniques.  Metabolon’s Global Discovery Panel is powered by the world’s largest proprietary metabolomics reference library.  Metabolon’s industry-leading data and translational science expertise help customers and partners address some of the most challenging and pressing questions in the life sciences, accelerating research and enhancing development success.  The company offers scalable, customizable multiomics solutions, including metabolomics and lipidomics, that support customer needs from discovery through clinical trials and product life-cycle management.  For more information, please visit www.metabolon.com and follow us on LinkedIn and Twitter.

About Metabolomics

Metabolomics, the large-scale study of all small molecules in a biological system, is the only omics technology that provides a complete current-state functional readout of a biological system.  Metabolomics helps researchers see beyond the genetic variation of individuals, capturing the combined impact of genetic and external factors such as the effect of drugs, diet, lifestyle, and the microbiome on human health. By measuring thousands of discrete chemical signals that form biological pathways in the body, metabolomics can reveal important biomarkers, enabling a better understanding of a drug’s mechanism of action, pharmacodynamics, and safety profile, as well as individual responses to therapy.

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References

1. Zgoda-Pols, J.R., et al., Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: investigation of nicotinic acid receptor agonists. Toxicol Appl Pharmacol, 2011. 255(1): p. 48-56.

2. Bryant, J.A., et al., The impact of an oral purified microbiome therapeutic on the gastrointestinal microbiome. Nat Med, 2026. 32(1): p. 186-196

3. McGovern, B .H., et al., SER-109, an Investigational Microbiome Drugto Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial. Clin Infect Dis, 2021. 72(12): p. 2132-2140.

4. Feuerstadt, P., et al., SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection. N Engl J Med, 2022. 386(3): p. 220-229.

5. Hu, Z., et al., Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer. Mol Oncol, 2025. 19(6): p. 1737-1750.

6. Butler, F.M., et al., Vegetarian Dietary Patterns and Diet-Related Metabolites Are Associated With Kidney Function in the Adventist Health Study-2 Cohort. J Ren Nutr, 2025.

7. Stanford, J., et al., Metabolomic Profiling and Diet Quality Scoring in a Randomized Crossover Trial of Healthy and Typical Dietary Patterns. Mol Nutr Food Res, 2025 . 69(23): p. e70271.

8. O’Connor, L.E., et al., Metabolomic Profiling of an Ultraprocessed Dietary Pattern in a Domiciled Randomized Controlled Crossover Feeding Trial. J Nutr, 2023. 153(8): p. 2181-2192.

9. Fritsch, D.A., et al., Microbiome function underpins the efficacy of a fiber-supplemented dietary intervention in dogs with chronic large bowel diarrhea. BMC Vet Res, 2022. 18(1): p. 245.

10. Leal, L.N., et al., Preweaning nutrient supply improves lactation productivity and reduces the risk of culling in Holstein cows. J Dairy Sci, 2025. 108(6): p. 5875-5888.

11. Ahsin, M., et al., Soil and pasture health underlie improved beef nutrient density determined by untargeted metabolomics in Southern US grass finished beef systems. NPJ Sci Food, 2025. 9(1): p. 151.

12. Yin, W., et al., Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia. J Lipid Res, 2012. 53(1): p. 51-65.

13. Porter, F .D., et al., Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease. Sci Transl Med, 2010. 2(56): p. 56ra81.

14. Needham, B .D., et al., Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder. Biol Psychiatry, 2021. 89(5): p. 451-462

15. Li, C., et al., Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells. J Exp Med, 2014. 211(1): p. 15-28.

16. Green, P.G., et al., Metabolic flexibility and reverse remodelling of the failing human heart. Eur Heart J, 2025. 46(25): p. 2422-2433.

17. Maekawa, H., et al., SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress. J Clin Invest, 2025. 135(19).

18. Wu, D., et al., Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition. Gut, 2026.

19. Schwerdtfeger, L.A., et al., Gut microbiota and metabolites are linked to disease progression in multiple sclerosis. Cell Rep Med, 2025. 6(4): p. 102055.

20. Wu, H., et al., Microbiome-metabolome dynamics associated with impaired glucose control and responses to lifestyle changes. Nat Med, 2025. 31(7): p. 2222-2231.

21. Jacobs, J.P., et al., Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome, 2021. 9(1): p. 236.

22. Pietzner, M., et al., Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. Nat Med, 2021. 27(3): p. 471-479.

23. Faquih, T.O., et al., Robust Metabolomic Age Prediction Based on a Wide Selection of Metabolites. J Gerontol A Biol Sci Med Sci, 2025. 80(3).

24. Scherer, N., et al., Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits. Nat Genet, 2025. 57(1): p. 193-205.

25. Holmes, Z.C., et al., Untargeted metabolomic analysis of human milk from healthy mothers reveals drivers of metabolite variability. Sci Rep, 2024. 14(1): p. 20827.

26. Titz, B., et al., Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases. Transl Vis Sci Technol, 2024. 13(6): p. 17.

27. Bloom, S.M., et al., Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation. Nat Microbiol, 2022. 7(3): p. 434-450.

28. Leimer, E.M., et al., Lipid profile of human synovial fluid following intra-articular ankle fracture. J Orthop Res, 2017. 35(3): p. 657-666.