Metabolon Verus™ Metabolomics Profiling Kit

A complete solution that delivers world-class metabolomics into your lab

Streamlined metabolomics workflows, data processing, and visualization tools to accelerate deep discovery

kits box and vials image

Metabolon Verus™ Metabolomics Profiling Kit

A complete solution that delivers world-class metabolomics into your lab

Streamlined metabolomics workflows, data processing, and visualization tools to accelerate deep discovery

kits box
scientist and Metabolon triangle

End-to-end metabolomics, simplified

The Metabolon Verus™ Metabolomics Profiling Kit provides a comprehensive, standardized workflow that allows you to focus on the science, not the complexity of data generation and processing.

Prepare samples

Streamlined, ready-to-use protocols ensure reproducibility across studies and laboratories.

~2 hrs hands-on

Run

Confirm your instrument is set up to acquire high-quality data with a quick system suitability test.

Perform broad metabolomic profiling using validated LC-MS methods and a curated reference library.

~30 min

Upload

Cloud-based pipelines convert raw spectral data into metabolite abundances with unmatched accuracy.

48 hrs processing

Data insights

Our Integrated Bioinformatics Platform unlocks biologically meaningful insights with no coding required. Pathway tools, statistics and multiomics integration are immediately accessible to all researchers.

5-day total TAT
scientist and Metabolon triangle

End-to-end metabolomics, simplified

The Metabolon Verus Metabolomics Profiling Kit provides a comprehensive, standardized workflow that allows you to focus on the science, not the complexity of data generation and processing.

End-to-End Metabolomics, Simplified

The Metabolon Verus Metabolomics Profiling Kit provides a comprehensive, standardized workflow that allows you to focus on the science, not the complexity of data generation and processing.

scientist and Metabolon triangle

Prepare samples

Streamlined, ready-to-use protocols ensure reproducibility across studies and laboratories.

~2 hrs hands-on

Run

Confirm your instrument is set up to acquire high-quality data with a quick system suitability test.

Perform broad metabolomic profiling using validated LC-MS methods and a curated reference library.

~30 min

Upload

Cloud-based pipelines convert raw spectral data into metabolite abundances with unmatched accuracy.

48 hrs processing

Data insights

Our Integrated Bioinformatics Platform unlocks biologically meaningful insights with no coding required. Pathway tools, statistics and multiomics integration are immediately accessible to all researchers.

5-day total TAT

Breaking through the barriers of metabolomics

Metabolomics has long forced a trade-off between throughput and accuracy. Complex method development, inconsistent quality, and slow processing have kept meaningful insights out of reach for most labs. The Verus™ Metabolomics Profiling Kit breaks through these barriers. Optimized methods, automated data processing, and rigorous built-in QA/QC combine into a single standardized workflow that any LC-MS lab can run with confidence.

Backed by more than two decades of metabolomics leadership, the Metabolon Verus™ Kit brings Metabolon-standard science directly to your hands. Scale seamlessly from pilot studies to large-scale cohorts and deliver reproducible, biologically meaningful data, with world-class bioinformatics tools that enable faster, deeper interpretation than any workflow available today.

More than

25

years of metabolomics leadership

More than

2 million

samples analyzed in Metabolon's state of the art research facility

More than

15,000

research projects delivered globally

More than

25

years of historically curated metabolomics data

Breaking through the barriers of metabolomics

Metabolomics has long forced a trade-off between throughput and accuracy. Complex method development, inconsistent quality, and slow processing have kept meaningful insights out of reach for most labs. The Verus™ Metabolomics Profiling Kit breaks through these barriers. Optimized methods, automated data processing, and rigorous built-in QA/QC combine into a single standardized workflow that any LC-MS lab can run with confidence.

Backed by more than two decades of metabolomics leadership, the Metabolon Verus™ Kit brings Metabolon-standard science directly to your hands. Scale seamlessly from pilot studies to large-scale cohorts and deliver reproducible, biologically meaningful data, with world-class bioinformatics tools that enable faster, deeper interpretation than any workflow available today.

More than

25

years of metabolomics leadership

More than

2 million

samples analyzed in Metabolon's state of the art research facility

More than

15,000

research projects delivered globally

More than

25

years of historically curated metabolomics data

Benefits of the Metabolon Verus™ Kit

Data you can trust
Metabolomic insights
Effortless workflows
Unified methods
Project management
female scientist works on data at a computer

Confident biological insights with reliable data

With the Metabolon Verus™ Metabolomics Profiling Kit, reliability is engineered into the workflow at every step. Every sample runs through a rigorously standardized, sample-specific method that ensures accuracy, precision, and high-confidence identification across plasma, serum, and urine.

Internal standards and mandatory QA/QC checkpoints validate system performance before and during every run, delivering reproducibility across plates, projects, and laboratories.

Metabolite identifications are highly accurate, enabled by Metabolon’s unmatched data processing experience and expertise. Each dataset meets the same uncompromising standards that have defined Metabolon’s leadership for over 25 years. The result is robust, reliable data that drive insights.

Gloved hand holds Metabolon reagent vial

From data to generation to insights within 5 days

The Metabolon Verus™ Metabolomics Profiling Kit leverages a library of over 1,500 metabolites across more than 100 sub-pathways, offering balanced coverage of xenobiotics, lipids, amino acid derivatives, bile acids, organic acids, and microbial–host co-metabolites. This depth enables researchers to explore major biological themes, including exposome and microbiome interactions, cardiometabolic regulation, inflammation, oxidative stress, and energy metabolism, with the context needed to understand how underlying pathways shift across conditions.

Backed by Metabolon’s extensive reference library and decades of biochemical knowledge, each dataset is delivered into our Integrated Bioinformatics Platform, supporting phenotype profiling, biomarker discovery, and tracking of disease or therapeutic response. The result is clear mechanistic insight, transforming complex metabolomic signals into meaningful biological understanding.

Metabolon Verus Kit box and reagent vials

Metabolomics expertise built right into the box

The Metabolon Verus™ Metabolomics Profiling Kit delivers biologically meaningful, QC-verified metabolomics insights in as little as five days, dramatically faster than traditional untargeted workflows. This efficiency is driven by analytical methods and data-processing pipelines refined over more than 25 years and validated across thousands of projects spanning a wide range of sample types.

Our secure processing system applies this accumulated knowledge, deploying machine-learning models to ensure consistent, high-quality outputs at scale. This depth of historical expertise is what makes accelerated turnaround possible without compromising rigor. Researchers can move from data acquisition to interpretation within five days, enabling timely, confident decision-making across studies of any size.

male scientist works at a mass spectrometer

Scalable workflows to fit your throughput

Metabolon Verus™ Metabolomics Profiling Kit is designed to support a wide range of scientific applications and programs across academic researchers, core facilities, and CROs. The workflow scales seamlessly from small pilot projects involving 15 samples to larger cohorts up to 1,500 samples, without sacrificing reproducibility or quality.

With the ability to run multiple biological matrices on a single plate, the kits offer unmatched versatility, enabling institutions to expand capacity and take on more complex projects without developing or optimizing new methods.

female scientist works with samples

A unified interface that simplifies every step

The Metabolon Verus™ Metabolomics Profiling Kit is supported by an intuitive online interface that centralizes everything you need to run high-quality metabolomics studies. Researchers gain full visibility into kit inventory and project status, along with integrated tools for manifest creation, balancing, plate mapping and data upload, ensuring every run is organized, traceable, and ready for analysis. System Suitability Test and Plate QC reports are generated automatically, providing immediate confirmation of instrument and workflow performance.

Once data acquisition is complete, automated data processing delivers results directly to the Integrated Bioinformatics Platform, where supporting materials, documentation, and access to the Metabolon Academy learning environment are readily available. This results in a seamless, end-to-end experience that minimizes manual effort and keeps your studies moving efficiently from preparation through interpretation.

Benefits of the Metabolon Verus™ Kit

Data you can trust
Metabolomic insights
Effortless workflows
Unified methods
Project management
female scientist works in lab at a computer

Confident biological insights with reliable data

With the Metabolon Verus™ Metabolomics Profiling Kit, reliability is engineered into the workflow at every step. Every sample runs through a rigorously standardized, sample-specific method that ensures accuracy, precision, and high-confidence identification across plasma, serum, and urine.

Internal standards and mandatory QA/QC checkpoints validate system performance before and during every run, delivering reproducibility across plates, projects, and laboratories.

Metabolite identifications are highly accurate, enabled by Metabolon’s unmatched data processing experience and expertise. Each dataset meets the same uncompromising standards that have defined Metabolon’s leadership for over 25 years. The result is robust, reliable data that drive insights.

gloved hand holds Verus Kit reagent vial

From data to generation to insights within 5 days

The Metabolon Verus™ Metabolomics Profiling Kit leverages a library of over 1,500 metabolites across more than 100 sub-pathways, offering balanced coverage of xenobiotics, lipids, amino acid derivatives, bile acids, organic acids, and microbial–host co-metabolites. This depth enables researchers to explore major biological themes, including exposome and microbiome interactions, cardiometabolic regulation, inflammation, oxidative stress, and energy metabolism, with the context needed to understand how underlying pathways shift across conditions.

Backed by Metabolon’s extensive reference library and decades of biochemical knowledge, each dataset is delivered into our Integrated Bioinformatics Platform, supporting phenotype profiling, biomarker discovery, and tracking of disease or therapeutic response. The result is clear mechanistic insight, transforming complex metabolomic signals into meaningful biological understanding.

Kit box open with vials

Metabolomics expertise built right into the box

The Metabolon Verus™ Metabolomics Profiling Kit delivers biologically meaningful, QC-verified metabolomics insights in as little as five days, dramatically faster than traditional untargeted workflows. This efficiency is driven by analytical methods and data-processing pipelines refined over more than 25 years and validated across thousands of projects spanning a wide range of sample types.

Our secure processing system applies this accumulated knowledge, deploying machine-learning models to ensure consistent, high-quality outputs at scale. This depth of historical expertise is what makes accelerated turnaround possible without compromising rigor. Researchers can move from data acquisition to interpretation within five days, enabling timely, confident decision-making across studies of any size.

male scientist works in lab

Scalable workflows to fit your throughput

The Metabolon Verus™ Metabolomics Profiling Kit is designed to support a wide range of scientific applications and programs across academic researchers, core facilities, and CROs. The workflow scales seamlessly from small pilot projects involving 15 samples to larger cohorts up to 1,500 samples, without sacrificing reproducibility or quality.

With the ability to run multiple biological matrices on a single plate, the kits offer unmatched versatility, enabling institutions to expand capacity and take on more complex projects without developing or optimizing new methods.

female scientist works in lab

A unified interface that simplifies every step

The Metabolon Verus™ Metabolomics Profiling Kit is supported by an intuitive online interface that centralizes everything you need to run high-quality metabolomics studies. Researchers gain full visibility into kit inventory and project status, along with integrated tools for manifest creation, balancing, plate mapping and data upload, ensuring every run is organized, traceable, and ready for analysis. System Suitability Test and Plate QC reports are generated automatically, providing immediate confirmation of instrument and workflow performance.

Once data acquisition is complete, automated data processing delivers results directly to the Integrated Bioinformatics Platform, where supporting materials, documentation, and access to the Metabolon Academy learning environment are readily available. This results in a seamless, end-to-end experience that minimizes manual effort and keeps your studies moving efficiently from preparation through interpretation.

IBP screenshot

Integrated Bioinformatics Platform

Once your kit run is complete, upload raw spectral data files to our secure cloud interface. Metabolon’s proprietary data processing pipeline delivers accurate metabolite identification results to the Integrated Bioinformatics Platform, where a suite of statistical and pathway tools enables researchers to explore results immediately.

The Bioinformatics Platform combines robust analyses and visualization tools such as PCA and volcano plots with pathway mapping, our proprietary Biomarker Lenses®, and statistics tools to uncover novel insights from your data and illustrate your findings in meaningful ways. The platform supports multi-user collaboration and enables researchers to integrate metabolomics data into multiomics research, facilitating advanced biological discovery.

Integrated Bioinformatics Platform

Once your kit run is complete, upload raw spectral data files to our secure cloud interface. Metabolon’s proprietary data processing pipeline delivers accurate metabolite identification results to the Integrated Bioinformatics Platform, where a suite of statistical and pathway tools enables researchers to explore results immediately.

The Bioinformatics Platform combines robust analyses and visualization tools such as PCA and volcano plots with pathway mapping, our proprietary Biomarker Lenses®, and statistics tools to uncover novel insights from your data and illustrate your findings in meaningful ways. The platform supports multi-user collaboration and enables researchers to integrate metabolomics data into multiomics research, facilitating advanced biological discovery.

IBP screenshot

Ready to bring Metabolon-standard metabolomics into your lab?

Register your interest in the Metabolon Verus™ Metabolomics Profiling Kit

Ready to bring Metabolon-standard metabolomics into your lab?

Register your interest in the Metabolon Verus™ Metabolomics Profiling Kit

References

1. Zgoda-Pols, J.R., et al., Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: investigation of nicotinic acid receptor agonists. Toxicol Appl Pharmacol, 2011. 255(1): p. 48-56.

2. Bryant, J.A., et al., The impact of an oral purified microbiome therapeutic on the gastrointestinal microbiome. Nat Med, 2026. 32(1): p. 186-196

3. McGovern, B .H., et al., SER-109, an Investigational Microbiome Drugto Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial. Clin Infect Dis, 2021. 72(12): p. 2132-2140.

4. Feuerstadt, P., et al., SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection. N Engl J Med, 2022. 386(3): p. 220-229.

5. Hu, Z., et al., Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer. Mol Oncol, 2025. 19(6): p. 1737-1750.

6. Butler, F.M., et al., Vegetarian Dietary Patterns and Diet-Related Metabolites Are Associated With Kidney Function in the Adventist Health Study-2 Cohort. J Ren Nutr, 2025.

7. Stanford, J., et al., Metabolomic Profiling and Diet Quality Scoring in a Randomized Crossover Trial of Healthy and Typical Dietary Patterns. Mol Nutr Food Res, 2025 . 69(23): p. e70271.

8. O’Connor, L.E., et al., Metabolomic Profiling of an Ultraprocessed Dietary Pattern in a Domiciled Randomized Controlled Crossover Feeding Trial. J Nutr, 2023. 153(8): p. 2181-2192.

9. Fritsch, D.A., et al., Microbiome function underpins the efficacy of a fiber-supplemented dietary intervention in dogs with chronic large bowel diarrhea. BMC Vet Res, 2022. 18(1): p. 245.

10. Leal, L.N., et al., Preweaning nutrient supply improves lactation productivity and reduces the risk of culling in Holstein cows. J Dairy Sci, 2025. 108(6): p. 5875-5888.

11. Ahsin, M., et al., Soil and pasture health underlie improved beef nutrient density determined by untargeted metabolomics in Southern US grass finished beef systems. NPJ Sci Food, 2025. 9(1): p. 151.

12. Yin, W., et al., Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia. J Lipid Res, 2012. 53(1): p. 51-65.

13. Porter, F .D., et al., Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease. Sci Transl Med, 2010. 2(56): p. 56ra81.

14. Needham, B .D., et al., Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder. Biol Psychiatry, 2021. 89(5): p. 451-462

15. Li, C., et al., Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells. J Exp Med, 2014. 211(1): p. 15-28.

16. Green, P.G., et al., Metabolic flexibility and reverse remodelling of the failing human heart. Eur Heart J, 2025. 46(25): p. 2422-2433.

17. Maekawa, H., et al., SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress. J Clin Invest, 2025. 135(19).

18. Wu, D., et al., Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition. Gut, 2026.

19. Schwerdtfeger, L.A., et al., Gut microbiota and metabolites are linked to disease progression in multiple sclerosis. Cell Rep Med, 2025. 6(4): p. 102055.

20. Wu, H., et al., Microbiome-metabolome dynamics associated with impaired glucose control and responses to lifestyle changes. Nat Med, 2025. 31(7): p. 2222-2231.

21. Jacobs, J.P., et al., Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome, 2021. 9(1): p. 236.

22. Pietzner, M., et al., Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. Nat Med, 2021. 27(3): p. 471-479.

23. Faquih, T.O., et al., Robust Metabolomic Age Prediction Based on a Wide Selection of Metabolites. J Gerontol A Biol Sci Med Sci, 2025. 80(3).

24. Scherer, N., et al., Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits. Nat Genet, 2025. 57(1): p. 193-205.

25. Holmes, Z.C., et al., Untargeted metabolomic analysis of human milk from healthy mothers reveals drivers of metabolite variability. Sci Rep, 2024. 14(1): p. 20827.

26. Titz, B., et al., Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases. Transl Vis Sci Technol, 2024. 13(6): p. 17.

27. Bloom, S.M., et al., Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation. Nat Microbiol, 2022. 7(3): p. 434-450.

28. Leimer, E.M., et al., Lipid profile of human synovial fluid following intra-articular ankle fracture. J Orthop Res, 2017. 35(3): p. 657-666.

Instrument Requirements

LC platform Waters Acquity I-Class UPLC
Thermo Vanquish Flex or Horizon
Mass spec platform Thermo Scientific Orbitraps
  • Tribrids (IDX/IQX)
  • Orbitrap Exploris series (120/240/480)
  • Q Exactive (Plus and UHMR)
More instruments to follow
Software required Xcalibur 4.2 or higher Freestyle 1.8 or higher Tune Software 2.11 or higher
Column (not included) Waters BEH C18 (2.1 × 100 mm, 1.7 µm) column is required for this kit (not included)

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