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Protected: Cecile Riviere-Cazaux – Developing a Liquid Biopsy Neuro-Oncology Toolkit

Published: June 16, 2025
In this interview, we speak with Cecile Riviere-Cazaux, an MD PhD candidate whose work bridges neurosurgery, clinical oncology, and multiomics to advance brain tumor research. Her focus lies in developing liquid biopsy techniques—using plasma, cerebrospinal fluid, and microdialysis—to improve monitoring and treatment response assessment in glioma patients. We explore the challenges of current imaging and biopsy methods, the promise of metabolomics and multiomics integration, and how these approaches could complement traditional diagnostics. Cecile Riviere-Cazaux also shares insights on translating these technologies into clinical practice and the future of personalized cancer care.

Cecile Riviere-Cazaux

Mayo Clinic
Cecile Riviere-Cazaux is an MD PhD candidate with expertise in liquid biopsy development in neuro-oncology, including evaluation of cell-free DNA (cfDNA), proteomics, and metabolomics, as well as early phase clinical trial development. She is a lead author of several studies that evaluate the ability to utilize cerebrospinal fluid and plasma as liquid biopsy sources to improve response assessment for patients with gliomas. The team’s studies have also evaluated how a technique known as microdialysis can be used within and outside of the operating room to evaluate the glioma in its environment, in situ. Her work bridges neurosurgery, clinical oncology, and multiomics approaches to develop a “toolkit” for disease monitoring and pharmacodynamic assessment in brain cancer.

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