Study Design Success Series

Your Guide to a Successful Metabolomic Study will equip researchers to leverage metabolomics in their labs and workflows for a variety of indications throughout the life sciences. In particular, we will cover how to select metabolites, targeted versus untargeted analysis, appropriate technology and instrumentation, study design, control versus variant analysis, sample types, sample preparation, and effective analysis of metabolomics results.

Read more

Before you embark on a metabolomics study, there are several important considerations you should make—especially if you are going to work with a vendor to complete your study. Here, we arm you with the most important questions you need to ask in order to find the right vendor and complete your metabolomics study with confidence.

Read more

Now that we’ve reviewed some of the most important considerations to make when deciding who to work with for your metabolomics studies (if you will not perform your studies in-house), it’s time to dive deep into the metabolomics study workflow. In this chapter, we provide an overview of each step in the workflow, from study design to data analysis and interpretation, and how Metabolon can help you each step of the way.

Read more

As we discussed in the previous chapter of this guide, conducting a successful metabolomics analysis and interpretation begins with a well-designed study. There are a number of factors to consider when designing your study to ensure your protocol delivers high-quality results for drawing actionable insights. In this chapter, we’ll go over each of these factors, breaking the process down into simple steps with clear, easy-to-follow advice.

Read more

In this chapter, we will take a closer look at the most common types of samples used in metabolomic studies. Many of the samples we will cover are human or animal in origin but can also include environmental samples, such as soil and water.

Read more

Regardless of the sample type, robust sample collection and transportation procedures must be established to preserve sample integrity. Failing to do so raises the risk of data variability, instrument interferences, and metabolite degradation. In this chapter, we provide an overview of the common steps underlying sample preparation, storage, and transportation.

Read more

Next comes the exciting moment when your data is returned! As you dive into the numbers, Metabolon scientists will help you turn your results into a story. In this chapter, we will go over the deliverables of your study analysis, interpretation, and insights.

Read more

You are now equipped to build a metabolomics experimental workflow; we encourage you to refer to the previous chapters of this guide at any time and contact us for further information. Here’s a quick review of the main points of discussion in each chapter that you can use to find what you need quickly.

Read more