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Large Scale Population Health Cohorts and the Value of Untargeted Metabolomics Data in Neurodegenerative and Kidney Disorders

Join Dr. Carlos Cruchaga, Ph.D., and Dr. Casey M. Rebholz, Ph.D. as they explore the relationships between genetics, genomics, disease, and metabolomics in this one-hour, two-session virtual seminar.

Large population studies offer the greatest opportunities to uncover the mechanisms of human biology.

Genome-wide association studies (GWAS) combined with metabolomics is a proven multi-omics model for greater biological insights. Investigators have demonstrated associations between metabolite biomarkers, genomic markers, and the onset of diseases or disorders.

In this webinar, we will share demonstrable outcomes from large-population, multi-omics studies and explore the roles of genomics and metabolomics as complementary statistical datasets.



Dr. Carlos Cruchaga, Ph.D.

Professor of Psychiatry, Washington University School of Medicine in St. Louis

Core Leader, Genetics & High Throughput – Omics, Knight Alzheimer Disease Research Center (ARDC),

Core Co-Leader, Genetics, The Dominantly Inherited Alzheimer Network (DIAN)

Scientific Advisor, McDonnell Genome Institute (MGI)

Director, NeuroGenomics and Informatics lab



Dr. Casey M. Rebholz, Ph.D.

Associate Professor of Epidemiology, Johns Hopkins Bloomberg School of Public Health Core Faculty, Welch Center for Prevention, Epidemiology, and Clinical Research



Heino Heyman, Ph.D.

Global Field Metabolomics Specialists Manager, Metabolon

Heino Heyman has been involved in Metabolomics for more than 10 years, starting in 2010 he worked on implementing metabolomics to develop quicker ways of finding active ingredients in natural products and better approaches of understanding hardy crops. In 2015 he joined the Integrative Omics team at Pacific Northwest National Lab, WA where he worked in the metabolomics group. Here he continued to apply metabolomics in several different fields, including human, microbial, plant, and soil metabolomics.

After his postdoc, he transitioned into the industry and joined Bruker Scientific, as a metabolomics applications specialist. At Bruker, he was prominent in promoting and showcasing solutions for customers using high-end ion-mobility mass spectrometry instrumentation addressing critical metabolomics problems. At the end of 2020, he joined Metabolon as a metabolomics application specialist to be involved in Metabolon’s leading metabolomics service and to get closer to the translational science that metabolomics informs.


Untargeted Metabolomics In Large Cohort Population Health Research - Neurodegenerative and Kidney Disorders


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