Contact us Demo our platform

We Are Metabolon

As the global leader in metabolomics, Metabolon’s mission is to deliver biochemical data and insights that expand and accelerate the impact of life sciences research in all its applications. We are committed to helping our customers address the most challenging and pressing questions to achieve their research objectives across biopharma, population health, consumer products, agriculture, wellness, and academic and government research sectors.

We have spent the last two decades developing industry-leading scientific, technology, and bioinformatics techniques, enabled by the world’s largest metabolomics reference library, to deliver actionable knowledge that drives effective decision-making. With 15,000+ projects completed, 4,000+ publications, and ISO 9001:2015, CLIA certifications, and CAP accreditation, we enable, accelerate, and support drug development through biomarker discovery, understanding mechanisms of action, patient stratification, and more.

Download Company Fact Sheet
Download Logo Files
Metabolon Press Kit

Corporate Headquarters

Research Triangle Park, NC

Founded

In 2000 by Dr. John Ryals and Dr. Paul Schimmel

Press Contact

pr@metabolon.com

Quick Links

Leadership
Publications
News

Unlocking Biochemistry with Metabolomics

Metabolomics, the large-scale study of all small molecules in a biological system, is the only ‘omics technology that provides a complete current-state functional readout of a biological system. Metabolomics helps researchers see beyond the genetic variation of individuals, capturing the combined impact of genetic and external factors such as the effect of drugs, diet, lifestyle, and the microbiome on human health. By measuring thousands of discrete chemical signals that form biological pathways in the body, metabolomics can help researchers understand what it means to be well and healthy and elucidate disease and other biological development mechanisms and markers. From a therapeutic perspective, metabolomics can reveal important biomarkers enabling a better understanding of potential therapeutic targets, biological and drug-related mechanisms of action, pharmacodynamics, and safety profiles, as well as individual responses to therapy.

Accelerating Life Science Research

Metabolon’s Global Discovery Panel leverages our market-leading platform and the world’s largest proprietary metabolomics reference library to quickly and accurately identify small molecule metabolites in a biological sample. With this data, our Data and Translational Science (DTS) experts help customers and partners worldwide address some of the most challenging and pressing questions in the life sciences, accelerating research and enhancing development success across the pharmaceutical, biotechnology, consumer products, agriculture, and nutrition industries, as well as academic and government organizations.

Metabolon has the ability to deliver unique and high-quality insights for our clients. We offer scalable, customizable metabolomics and lipidomics solutions delivering relative and absolute quantitative bioanalytical data, biomarker discoveries and innovative diagnostic tests to support customer needs from discovery through clinical trials and product life-cycle management.

Download Services Photos

Our Commitment to Quality

All standardized procedures we perform, including method design and development, validation, equipment management, non-conformance management, and all sample handling and analytical testing procedures are governed by an ISO 9001:2015 certified quality management system. Metabolon also incorporates quality control steps at every stage of testing to ensure the highest quality data.

Expertise

45+ PhDs

Proprietary Metabolite Library

5,400+

Publications

4,000+

Our People

We value diversity of background and mindset just as highly as expertise and technical knowledge. Our team works tirelessly every day to enable scientific discoveries that make a difference. We are committed to hard work, excellence, and success through collaboration at every level. Our shared devotion to being the best at what we do and to making a positive difference unites the contribution of every individual. These are the characteristics of our values: Purpose, Passion, and Performance.

Download Leadership Team Photos
Download Leadership Team Bios
MetabolonOurPeople

GET STARTED

Talk with an expert

Request a quote, get detailed information on sample types, or learn how metabolomics can accelerate your research. Find our contact details are here.

Find us on:

Talk with a Metabolomics expert

✕

References

1. Zgoda-Pols, J.R., et al., Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: investigation of nicotinic acid receptor agonists. Toxicol Appl Pharmacol, 2011. 255(1): p. 48-56.

2. Bryant, J.A., et al., The impact of an oral purified microbiome therapeutic on the gastrointestinal microbiome. Nat Med, 2026. 32(1): p. 186-196

3. McGovern, B .H., et al., SER-109, an Investigational Microbiome Drugto Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial. Clin Infect Dis, 2021. 72(12): p. 2132-2140.

4. Feuerstadt, P., et al., SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection. N Engl J Med, 2022. 386(3): p. 220-229.

5. Hu, Z., et al., Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer. Mol Oncol, 2025. 19(6): p. 1737-1750.

6. Butler, F.M., et al., Vegetarian Dietary Patterns and Diet-Related Metabolites Are Associated With Kidney Function in the Adventist Health Study-2 Cohort. J Ren Nutr, 2025.

7. Stanford, J., et al., Metabolomic Profiling and Diet Quality Scoring in a Randomized Crossover Trial of Healthy and Typical Dietary Patterns. Mol Nutr Food Res, 2025 . 69(23): p. e70271.

8. O’Connor, L.E., et al., Metabolomic Profiling of an Ultraprocessed Dietary Pattern in a Domiciled Randomized Controlled Crossover Feeding Trial. J Nutr, 2023. 153(8): p. 2181-2192.

9. Fritsch, D.A., et al., Microbiome function underpins the efficacy of a fiber-supplemented dietary intervention in dogs with chronic large bowel diarrhea. BMC Vet Res, 2022. 18(1): p. 245.

10. Leal, L.N., et al., Preweaning nutrient supply improves lactation productivity and reduces the risk of culling in Holstein cows. J Dairy Sci, 2025. 108(6): p. 5875-5888.

11. Ahsin, M., et al., Soil and pasture health underlie improved beef nutrient density determined by untargeted metabolomics in Southern US grass finished beef systems. NPJ Sci Food, 2025. 9(1): p. 151.

12. Yin, W., et al., Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia. J Lipid Res, 2012. 53(1): p. 51-65.

13. Porter, F .D., et al., Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease. Sci Transl Med, 2010. 2(56): p. 56ra81.

14. Needham, B .D., et al., Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder. Biol Psychiatry, 2021. 89(5): p. 451-462

15. Li, C., et al., Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells. J Exp Med, 2014. 211(1): p. 15-28.

16. Green, P.G., et al., Metabolic flexibility and reverse remodelling of the failing human heart. Eur Heart J, 2025. 46(25): p. 2422-2433.

17. Maekawa, H., et al., SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress. J Clin Invest, 2025. 135(19).

18. Wu, D., et al., Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition. Gut, 2026.

19. Schwerdtfeger, L.A., et al., Gut microbiota and metabolites are linked to disease progression in multiple sclerosis. Cell Rep Med, 2025. 6(4): p. 102055.

20. Wu, H., et al., Microbiome-metabolome dynamics associated with impaired glucose control and responses to lifestyle changes. Nat Med, 2025. 31(7): p. 2222-2231.

21. Jacobs, J.P., et al., Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome, 2021. 9(1): p. 236.

22. Pietzner, M., et al., Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. Nat Med, 2021. 27(3): p. 471-479.

23. Faquih, T.O., et al., Robust Metabolomic Age Prediction Based on a Wide Selection of Metabolites. J Gerontol A Biol Sci Med Sci, 2025. 80(3).

24. Scherer, N., et al., Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits. Nat Genet, 2025. 57(1): p. 193-205.

25. Holmes, Z.C., et al., Untargeted metabolomic analysis of human milk from healthy mothers reveals drivers of metabolite variability. Sci Rep, 2024. 14(1): p. 20827.

26. Titz, B., et al., Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases. Transl Vis Sci Technol, 2024. 13(6): p. 17.

27. Bloom, S.M., et al., Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation. Nat Microbiol, 2022. 7(3): p. 434-450.

28. Leimer, E.M., et al., Lipid profile of human synovial fluid following intra-articular ankle fracture. J Orthop Res, 2017. 35(3): p. 657-666.