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The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors

Author: Mark Watson, Anne Roulston, Laurent Bélec, Xavier Billot, Richard Marcellus, Dominique Bédard, Cynthia Bernier, Stéphane Branchaud, Helen Chan, Kenza Dairi, Karine Gilbert, Daniel Goulet, Michel-Olivier Gratton, Henady Isakau, Anne Jang, Abdelkrim Khadir, Elizabeth Koch, Manon Lavoie, Michael Lawless, Mai Nguyen, Denis Paquette, Émilie Turcotte, Alvin Berger, Matthew Mitchell, Gordon C. Shore, Pierre Beauparlant
Year Published: 2009
Media Outlet: Molecular and Cellular Biology

Open Access? No

Matrix: Tissue
Biological Themes: Energetics
Product(s): Global Discovery Panel
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