Presentation: Leveraging Global Metabolomics at the Intersection of Physiology and Behavior (at MANA 2020)
12:00 pm EDT
Metabolomics offers researchers the ability to get closer to the phenotype by identifying small molecules and combining these results with bioinformatic and biochemical expertise, producing actionable insights. Metabolon’s Precision Metabolomics™ LC-MS global metabolomics platform provides a high-fidelity, reproducible analysis of the current-state of a biological system to reveal changes in key biological pathways.
As the interest in and understanding of sports-related head injuries continues to grow, Nicole Vike and Sumra Bari will share small molecule insights to better characterize these injuries. Drs. Vike and Bari have integrated metabolomic data with other technologies such as resting state fMRI, transcriptomics and computational behavior using a virtual reality task, to assess effects of exposure to head acceleration events (HAEs). These findings not only provide exciting insights into the mechanism and monitoring of HAEs, but also provide examples of integration of metabolomics with other data streams to fuel physiological discoveries.