About Us

Metabolon, headquartered in Research Triangle Park, NC, is a diagnostic products and services company offering the industry’s leading biochemical profiling platform. Our patented platform provides a global analysis of complex biological samples for the discovery of markers and pathways associated with drug action and disease. This differentiated approach enables the identification of biomarkers useful for the development of a wide range of diagnostics and provides insight into complex biochemical processes such as drug action, toxicology and bioprocess optimization.

Core Technology
Metabolon has developed and patented technology and methodologies that simultaneously detect and quantify all of the small molecules present in complex biological specimens. This is extremely important because these small molecules represent the products of cellular metabolism, which change in response to disease and drug therapy.

One of the major advantages of this approach is the vast amount of biochemical information that has been assembled from 100 years of biochemical research. Leveraging this knowledge base, we can more easily discover biochemical biomarkers that can be used to readily identify pathways and targets involved in disease and drugs. The unique advantage of the biomarkers discovered by Metabolon is that biochemical markers represent changes which are truly indicative of the drug action or disease mechanisms and is generally not achieved through other approaches, such as transcriptomics or proteomics.

Metabolon’s technology is extremely robust and has been rigorously tested and validated as a powerful tool for discovery of biomarkers of disease, drug efficacy, drug toxicity and mechanism of action in clinical specimens by over 1500+ studies with pharmaceutical, government and academic investigators.

Products and Services

Fee-For-Service Business
Metabolon’s fee-for-service business is focused on product-based global biochemical profiling solutions provided to pharmaceutical and biotechnology companies as well as funded government and academic institutions engaged in product development activities.

We provide comprehensive biochemical profiling for a wide variety of applications, including drug safety and efficacy studies, bioprocess optimization and consumer product development. We are currently working with 14 of the top 15 pharmaceutical companies and many biotechnology companies.

Please click here to learn more about Metabolon’s Academic, Pharma/Biotech, or Consumer Products Services business.

Diagnostic Products Business
Built upon our core biomarker discovery engine, Metabolon is focused on developing, validating and marketing molecular diagnostic assays for the detection and monitoring of disease based in part upon biomarkers discovered from its collaborative and fee-for-service studies. These novel biochemical biomarkers provide the basis for its diagnostic products.

To develop innovative and relevant molecular diagnostic assays, Metabolon focuses biomarker discovery, targeted assay development and clinical validation studies in diseases where treatment costs and costs associated with treatment failure are high and current diagnostic methods are expensive, invasive or lack predictive power for accurate diagnosis, prognosis or therapeutic monitoring of disease.

Please click here to learn more about Metabolon’s Diagnostic business.

For more information about Metabolon, please contact us.